论文部分内容阅读
为探讨补充肌酸对提高大鼠运动能力的作用，观察了肌酸对游泳大鼠骨骼肌代谢的影响。本实验取雄性Ｗｉｓｔａｒ大鼠２４只，随机分为正常对照组、游泳对照组和游泳＋补充肌酸组。两个游泳组每天游泳训练１ｈ，９天后， 游泳４ｈ，测定血乳酸和尿素氮水平，测定骨骼肌乳酸、糖原和线粒体脂质过氧化物（ＬＰＯ）水平、线粒体膜的流动性以及线粒体矿物元素钙（Ｃａ）、镁（Ｍｇ）、钾（Ｋ）含量。结果显示：肌酸可抑制游泳运动后大鼠的血乳酸浓度、血清尿素氮、骨骼肌乳酸、线粒体ＬＰＯ的升高幅度，抑制骨骼肌糖原、线粒体膜流动性和矿物质元素Ｃａ、Ｍｇ、Ｋ含量的下降。以上结果表明，肌酸可改善运动后骨骼肌线粒体功能。
In order to investigate the effect of creatine supplementation on improving motor performance in rats, the effect of creatine on skeletal muscle metabolism in swimming rats was observed. Twenty-four male Wistar rats were randomly divided into normal control group, swimming control group and swimming plus supplemental creatine group. The swimming groups were trained to swim for 1 hour, 9 days and 4 hours respectively. The levels of lactate, glycogen and mitochondrial lipid peroxide (LPO), the fluidity of mitochondrial membrane and the mitochondrial mineral content Elements of calcium (Ca), magnesium (Mg), potassium (K) content. The results showed that creatine could inhibit the level of blood lactate, serum urea nitrogen, skeletal muscle lactate and mitochondrial LPO in swimming rats, inhibit the glycogen of skeletal muscle, mitochondrial membrane fluidity and the contents of Ca, Mg, K content decreased. The above results show that creatine can improve skeletal muscle mitochondrial function after exercise.