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目的:分析上海市闵行区不同级别医院口服降糖药用药特点,为临床合理用药提供参考。方法:采用回顾性分析方法,对区内16家医院2015年12月—2016年11月口服降糖药用药金额、用药频度(DDDs)及日均费用(DDC)等指标进行统计分析。结果:2015年12月—2016年11月本区口服降糖药购药总金额6 751.05万元,其中一级医院占76.89%,阿卡波糖在一、二、三级医院分别排名第1。一级医院有5个品种购药金额在300~800万元之间,格列吡嗪控释片排名第2。瑞格列奈购药金额在二、三级医院排名第2。一级医院二甲双胍用药频度最高为834.02万日。DDC最高为阿卡波糖在一、二、三级医院分别排名第1,沙格列汀在二、三级医院排名第2。一、二、三级医院用药一致性为28.13%。结论:我区糖尿病患者主要在社区配药,医生和患者更趋向选择基本药物,价格合理,一、二级医院用药品规更接近。
Objective: To analyze the characteristics of oral hypoglycemic agents in different levels of hospitals in Minhang District, Shanghai, and to provide reference for clinical rational use of drugs. Methods: The retrospective analysis was used to analyze the oral hypoglycemic drugs dosage, DDDs and DDC in 16 hospitals from December 2015 to November 2016 in our hospital. Results: From December 2015 to November 2016, the total amount of oral hypoglycemic agents purchased in the district totaled 67.5105 million yuan, of which 76.89% were in first-class hospitals. Acarbose ranked first in the first, second and third-tier hospitals respectively . A hospital has five varieties of medicines in the amount of 300 to 800 million between the glipizide controlled release tablets ranked No. 2. The amount of repaglinide in the second and third hospitals ranked No. 2. First-class hospital metformin frequency of up to 8.34 million. DDC up to acarbose in the first, second and third hospitals were ranked No. 1, saxagliptin ranked second in the second and third hospitals. First, second and third level hospital medication consistency was 28.13%. Conclusion: The diabetic patients in our district mainly distribute drugs in the community. Doctors and patients tend to choose the essential drugs at reasonable prices. The prescriptions of drugs in the first and second level hospitals are closer to each other.