选择性 IgA 缺乏症是儿科较为常见的体液免疫缺陷病,由于该病具有多样化的症状,加之实验室检测手段不够完善,临床易致误诊。笔者近收治1例,报告如下:患者女,8个月。反复发烧、咳嗽、喘、腹泻4个月久治不愈来诊。患者系第一胎,母乳喂养。母患慢性气管炎3年,类风湿性关节炎5年。查体:体温38.4℃,脉搏118次,呼吸30次。营养中等,发育差。呼吸浅促,轻度方颅,咽充血,扁桃体Ⅱ度肿大。两肺中下部可闻中、小水泡音。肝大右肋下3cm,肠鸣音轻度增强。白细胞6400,中性56%,淋巴42%,嗜酸性1%;红细胞360万,血红蛋白8g;总蛋白5g,其它无异 Selective IgA deficiency is a common pediatric humoral immune deficiency disease, due to the disease has a variety of symptoms, combined with laboratory testing methods are not perfect enough, clinical misdiagnosis. I nearly received treatment in 1 case, the report is as follows: Female patient, 8 months. Repeated fever, cough, asthma, diarrhea 4 months long treatment. The patient is the first child to breastfeed. Motherhood suffering from chronic bronchitis 3 years, rheumatoid arthritis 5 years. Physical examination: body temperature 38.4 ℃, pulse 118 times, breathing 30 times. Medium nutrition, poor development. Shortness of breath, mild square cranial pharynx congestion, tonsil Ⅱ degree enlargement. Middle and lower lungs can be heard, small blisters sound. Large right rib ribs 3cm, mild bowel sounds enhancement. White blood cells 6400, 56% neutral, lymphatic 42%, eosinophilic 1%; erythrocyte 3.6 million, hemoglobin 8g; total protein 5g, the other no difference