近年来,临床抗感染治疗面临的挑战不断增加。由多重耐药菌引起的院内感染严重影响了医疗安全和患者安全,更值得关注的是,多重耐药菌的发生率正逐年升高,多重耐药菌院内感染已成为延长患者住院时间、增加医疗费用和导致患者死亡的重要原因,有效快速地控制感染是降低患者病死率的关键。因此,有效控制细菌耐药性,推广合理使用抗菌药势在必行。当前,抗生素不合理应用导致“超级细菌”滋生,全球对“超级细菌”疫情的暴发忧心忡忡。作为抗生素生产 In recent years, the challenges facing clinical anti-infective treatment are constantly increasing. Hospital infections caused by multiple drug-resistant bacteria have seriously affected the medical safety and patient safety. What deserves more attention is that the incidence of multi-drug resistant bacteria is increasing year by year. Infection with multi-drug resistant bacteria has become an extension of hospitalization time and increased Medical costs and the leading cause of death of patients, effective and rapid control of infection is the key to reducing patient mortality. Therefore, it is imperative to effectively control bacterial resistance and promote the rational use of antibacterials. At present, the unreasonable application of antibiotics leads to the breeding of “super bacteria” and the global concern over the outbreak of “super bacteria”. Produced as antibiotics