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目的:探讨68例多发性骨髓瘤MM患者的临床首发症状,实验室相关检查特点。方法:回顾分析我院2002年1月～2012年3月期间68例MM患者临床表现及实验室相关资料。结果:68例MM患者中临床表现具有多样性,细胞形态学检查中骨髓瘤细胞比例大于20%的占76%,骨髓瘤细胞比例小于20%的占24%,骨髓中成熟红细胞呈缗钱状排列者占78%,血清蛋白电泳中53例患者出现M蛋白,免疫球蛋白IgG增高15例,IgA增高11例,轻链型4例,X线检查结果 48例提示骨质有异常改变。结论:临床表现和实验室检查对明确诊断MM及早期治疗都有很重要的意义。
Objective: To investigate the clinical first symptom of 68 MM patients with multiple myeloma and laboratory related features. Methods: A retrospective analysis of our hospital from January 2002 to March 2012 68 cases of MM clinical manifestations and laboratory-related data. Results: The clinical manifestations of 68 MM patients were diverse. The proportion of myeloma cells in cell morphology was more than 20% in 76%, the percentage of myeloma cells was less than 20% in 24%, and the mature erythrocytes in bone marrow Among them, 78 cases were arranged, 53 cases of M protein in serum protein electrophoresis, 15 cases of IgG increased, 11 cases of IgA increased, 4 cases of light chain and 48 cases of abnormal X-ray examination. Conclusion: Clinical manifestations and laboratory tests are of great importance in the diagnosis of MM and early treatment.