本文在Ｂ超引导下经皮肝穿刺，将无水酒精和抗癌药物同时直接注入癌灶内治疗５例晚期原发性肝癌，注射后肿瘤缩小，甲胎蛋白（ＡＦＰ）不同程度下降，Ｂ超下癌灶内出现“结石样”强回声光团，细胞学查证实为变性，坏死的癌细胞。全部病例生存期超过６个月。此法操作简便，经济安全，不良反应少，疗效明显，值得进一步推广应用。 This article under the guidance of B-ultrasound percutaneous transhepatic injection of alcohol and anti-cancer drugs into the cancer foci at the same time in the treatment of 5 cases of advanced primary liver cancer, tumor shrinkage after injection, alpha-fetoprotein (AFP) to varying degrees, B A “stone-like” strong echogenic light mass appeared in the super cancerous area. Cytological examination confirmed that it was denatured and necrotic cancer cells. All cases survived for more than 6 months. This method is easy to operate, economical and safe, with few adverse reactions and obvious curative effect. It is worth further promotion and application.