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目的：用离体兔肺连续温血再灌注模型评价低温保存后供体肺功能。方法：将未经灌洗和保存的对照组（ｎ＝６）供体左肺，与低温１０℃下保存１８小时后的实验组（ｎ＝６）供体左肺，分别在离体状态下，连续通气和温静脉血灌注３０分钟，将离体左肺引流出的动脉血，泵入另一兔体内，通过交叉循环使之静脉化后连续再灌注。结果：对照组氧分压显著优于实验组，两组间的肺动脉平均压、呼吸道峰压及再灌注后离体肺的湿／干重量比率结果无显著性差异。结论：该方法的建立为供体肺保存的研究提供了较理想的动物模型。
OBJECTIVE: To evaluate the donor’s lung function after cryopreserved by continuous rabbit lung perfusion model. Methods: The left lung of the control group (n = 6) without donor and preservation, and the experimental group (n = 6) donor left lung after preservation for 18 hours at 10 ℃, respectively. , Continuous ventilation and warm venous perfusion for 30 minutes, the left pulmonary artery drainage from the body, pumped into another rabbit body, through the cross-circulation of venous after continuous reperfusion. Results: The partial pressure of oxygen in the control group was significantly better than the experimental group. There was no significant difference between the two groups in the mean pulmonary artery pressure, the peak airway pressure and the wet / dry weight ratio of isolated lung after reperfusion. Conclusion: The establishment of this method provides an ideal animal model for the study of donor lung preservation.