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洋金花为白花曼陀罗的花,平喘镇咳、镇痛、解痉,用于哮喘咳嗽、脘腹冷痛、小儿慢惊、外科麻醉等,其主要有效成分为莨菪烷类生物碱,总碱含量0.47～0.75％,其中东莨菪碱含量较高。本制剂以洋金花生物碱成分为主制成简便易用的新剂型涂膜剂,用于治疗风湿痹痛,具解痉消炎的功效。以酸性染比色法测得中间产物洋金花流浸膏的总碱含量。操作简便,灵敏可靠,可作为制剂的内控指标,以控制成品质量。
Yang Jinhua is a white flower Datura flower, antitussive, antitussive, analgesic, antispasmodic, for asthma cough, cold abdominal pain, pediatric panic attacks, surgical anesthesia, its main active ingredient is tropane alkaloids The total alkali content was 0.47-0.75%, of which the scopolamine content was higher. The preparation is made from the alkaloid composition of Datura fragrans as an easy-to-use new agent-type coating agent for the treatment of rheumatism and analgesia, and has the effect of anti-inflammatory and anti-inflammatory. The total alkali content of the intermediate product D. grandiflora extract was measured by an acid dye colorimetric method. The operation is simple, sensitive and reliable, and can be used as an internal control indicator of the preparation to control the quality of the finished product.