双侧颈总动脉及左侧椎动脉结扎造成兔不完全性脑缺血。Ｂｅｒ在体外能显著抑制胶原，ＡＤＰ和ＡＡ诱导的脑缺血兔血小板聚集，ＩＣ５０分别为０．１５，０．４６和０．５１ｍｇ·ｍｌ１。兔脑缺血３０ｍｉｎ后，ｉｖＢｅｒ５ｍｇ·ｋｇ１能使胶原诱导的血小板聚集程度降低；而ｉｖＢｅｒ２５，或５０ｍｇ·ｋｇ１，９０ｍｉｎ后，可使胶原、ＡＤＰ和ＡＡ诱导的血小板聚集程度明显降低。Ｂｅｒ能显著降低脑缺血兔ＴＸＢ２的血浆水平，但６酮前列腺素Ｆ１α变化不明显。提示Ｂｅｒ致血浆血栓素Ｂ２水平下降是其抗脑缺血作用机制之一 Bilateral carotid artery and left vertebral artery ligation caused incomplete rabbit cerebral ischemia. Ber in vitro can significantly inhibit collagen, ADP and AA-induced platelet aggregation in ischemic rabbit, IC50 were 0.15,0.46 and 0.51mg · ml 1. After 30min ischemia, ivBer5mg · kg1 can reduce the degree of collagen-induced platelet aggregation; and ivBer25, or 50mg · kg1,90min, can collagen, ADP and AA-induced platelet aggregation decreased significantly. Ber can significantly reduce the plasma levels of TXB2 in ischemic rabbit, but the change of 6-ketoprostaglandin F1α is not obvious. Tip Ber induced plasma thromboxane B2 level is one of its anti-cerebral ischemia mechanism