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乙型肝炎疫苗(HepB)接种是阻断乙型肝炎病毒(HBV)传播、预防乙型肝炎的最有效方法。HepB可以分为预防性疫苗和治疗性疫苗。本文综述了HepB及其佐剂的研究新进展,指出乙型肝炎治疗性疫苗以及新型疫苗佐剂是当前HepB研究的重要方向。此外,针对HepB的免疫不良反应和无(弱)应答问题提出应对措施。
Hepatitis B vaccine (HepB) vaccination is the most effective way to block the spread of Hepatitis B virus (HBV) and prevent Hepatitis B. HepB can be divided into preventive and therapeutic vaccines. This review summarizes the recent advances in HepB and its adjuvants and points out that therapeutic vaccines for hepatitis B and new vaccine adjuvants are important directions for HepB research. In addition, the response to HepB’s immune adverse reactions and no (weak) response to countermeasures.