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软胶囊亦称弹性胶囊,其弹性的大小取决于囊壳的明胶、增塑剂和水三者的比例。最早的软胶囊制剂有维生素A、D胶丸,自1933年Scherer发明了旋转冲模包囊机,使产量大大提高。成本大幅下降,欧美各国纷纷采用,并不断对机械设备作出改进,使胶囊不仅能填装液体、糊状软体药物,又发展到能填装固体粉末,颗粒等,品种和产量不断增加。软胶囊制剂由于具有生物利用度好,密封、安全,药剂稳定,剂量准确,外形美观,携带和使用方便等特点,因此越来越受到消费者的青睐,国内外市场前景广阔,发展潜力巨大。
Soft capsules are also called elastic capsules, and their elasticity depends on the ratio of gelatin, plasticizer and water in the capsule shell. The earliest soft capsule preparations were vitamin A and D capsules. Since 1933 Scherer invented a rotary die crusher, which greatly increased the output. The cost has dropped dramatically. Countries in Europe and the United States have adopted and continuously improved the machinery and equipment so that capsules can not only fill liquid and paste-like soft drugs, but also can be filled with solid powders, granules, etc., and the variety and output are increasing. Soft capsules are favored by consumers because of their good bioavailability, sealing, safety, stable medicaments, accurate dosage, beautiful appearance, convenient carrying and use, etc. The domestic and foreign markets have broad prospects and huge potential for development.