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目的观察小牛脾提取物注射液联合吉西他滨加顺铂方案治疗晚期非小细胞肺癌的疗效及毒副作用。方法 60例晚期非小细胞肺癌患者随机分为两组:对照组采用吉西他滨加顺铂方案化疗;治疗组化疗方案同对照组,并同时给予小牛脾提取物注射液静脉滴注。21天为1个周期。结果治疗组白细胞减少,血小板减少低于对照组(P<0.01),生活质量改善优于对照组(P<0.05)。结论小牛脾提取物注射液联合化疗治疗晚期非小细胞肺癌能减轻毒副反应,改善患者的生活质量。
Objective To observe the curative effect and toxicity of calf spleen extract combined with gemcitabine plus cisplatin in the treatment of advanced non-small cell lung cancer. Methods Sixty patients with advanced non-small cell lung cancer were randomly divided into two groups: the control group received gemcitabine and cisplatin chemotherapy; the chemotherapy group and the control group received intravenous infusion of calf spleen extract injection. 21 days for a cycle. Results The leukopenia and thrombocytopenia in the treatment group were lower than those in the control group (P <0.01), and the quality of life improvement was better than that in the control group (P <0.05). Conclusion Calf spleen extract injection combined with chemotherapy for advanced non-small cell lung cancer can reduce the side effects and improve the quality of life of patients.