论文部分内容阅读
目的探讨对胰岛素治疗老年糖尿病患者进行院外全程用药指导的临床效果。方法 120例老年糖尿病患者,根据不同的用药指导方式分为观察组和对照组,每组60例。对照组采用传统的用药指导,观察组在对照组基础上进行院外全程用药指导。1年后观察两组患者血糖的控制情况和不良反应发生率。结果干预后,观察组患者空腹血糖(6.73±1.7)mmol/L,低于对照组(9.16±2.64)mmol/L,差异有统计学意义(P<0.05)。干预后,观察组患者餐后2 h血糖(7.25±2.33)mmol/L,低于对照组(10.55±2.52)mmol/L,差异有统计学意义(P<0.05)。观察组患者中发生不良反应的患者2例,包括低血糖反应1例,酮症酸中毒1例,不良反应发生率为3.3%;对照组患者中发生不良反应的患者8例,包括低血糖反应4例,高血糖反应2例,酮症酸中毒2例,不良反应发生率为13.3%;观察组不良反应发生率明显低于对照组,差异有统计学意义(P<0.05)。结论对胰岛素治疗老年糖尿病患者进行院外全程用药指导,可以较好地控制患者的血糖,能降低不良反应,提高治疗效果,改善患者的生活质量。
Objective To investigate the clinical effect of insulin therapy on elderly patients with diabetes mellitus during the whole course of medication guidance. Methods One hundred and twenty cases of elderly diabetic patients were divided into observation group and control group according to different medication guidance methods, 60 cases in each group. The control group using traditional medicine guidance, the observation group on the basis of the control group to guide the whole hospital outside the medication. One year later, the control of blood glucose and the incidence of adverse reactions were observed in both groups. Results After intervention, the fasting blood glucose (6.73 ± 1.7) mmol / L in the observation group was significantly lower than that in the control group (9.16 ± 2.64 mmol / L) (P <0.05). After intervention, the 2 h postprandial plasma glucose (7.25 ± 2.33) mmol / L in the observation group was significantly lower than that in the control group (10.55 ± 2.52 mmol / L) (P <0.05). Two patients in the observation group had adverse reactions, including 1 hypoglycemic reaction, 1 ketoacidosis, and 3.3% adverse reactions. In the control group, 8 patients had adverse reactions including hypoglycemia 4 cases, 2 cases of hyperglycemia, ketosis acidosis in 2 cases, the incidence of adverse reactions was 13.3%; adverse reaction rate was significantly lower than the control group, the difference was statistically significant (P <0.05). Conclusion Insulin treatment of elderly patients with diabetes medication guidance throughout the hospital can better control the patient’s blood sugar, can reduce adverse reactions, improve the therapeutic effect and improve the quality of life of patients.