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以不同耐力负荷的雄性Ｗｉｓｔａｒ大鼠心脏为研究对象，采用酶组织化学、常规组织学的ＨＥ．Ｍａｓｓｏｎ和心肌闰盘特异性染色等方法及电镜技术，对不同耐力负荷下乳头肌及心内膜下心肌组织结构变化与心肌功能的适应性做了观察。结果表明，适宜的耐力负荷可使乳头肌细胞肥大，毛细血管数量增加，心肌窦样管及与心腔相通的管道扩张；不适宜的超量负荷及耗竭训练导致乳头肌及毛细血管、心肌窦样管和与心腔管道缩窄或闭锁，造成乳头肌细胞缺血缺氧性损伤，损伤程度与运动负荷关系密切。
The hearts of male Wistar rats with different endurance load were used as study objects, using enzyme histochemistry and routine histology HE. Masson and myocardial intercalated disc specific staining methods and electron microscopy techniques, the endurance of papillary muscles and subendocardial tissue structure changes and myocardial function adaptability were observed under different endurance load. The results show that appropriate endurance load can make papillary muscle cells hypertrophy, the number of capillaries increased, cardiac sinus tube and the heart chamber connected to the expansion of the pipeline; unsuitable overloading and exhaustion training lead to papillary muscles and capillaries, myocardial sinus Sympathetic and cardiac cavities narrowed or blocked, resulting in hypoxic ischemic damage of papillary muscle cells, the degree of injury and exercise load are closely related.