氟中毒的基本病因已清楚是机体长期摄入过量氟所引起的以氟斑牙和氟骨症为特征的全身性慢性疾病,氟斑牙主要表现为牙体硬组织色素沉着,显色斑,同时牙齿硬度减弱,易碎裂。氟骨症的临床症状有腰部及四肢关节疼痛,活动障碍,骨骼变形,甚至瘫痪,严重危害人群的健康。氟骨症中骨组织 The basic etiology of fluorosis has been clearly chronic body disease characterized by fluorosis and fluorosis as a result of excessive intake of fluoride in the body over a long period of time. Dental fluorosis mainly manifests as dental hard tissue pigmentation, At the same time the hardness of the teeth is weakened and fragile. The clinical symptoms of skeletal fluorosis include lumbar and limb joint pain, movement disorders, skeletal deformities, and even paralysis, which seriously endanger the health of the population. Bone tissue in skeletal fluorosis