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目的 利用因子分析显像对原发性肝细胞癌(HCC)进行定性、定位诊断研究。方法 对正常16 例,HCC 13 例,肝海绵状血管瘤21 例经肘静脉“弹丸”方式注入99m Tc 洗脱液370 MBq(体积< 1 m l)后,立刻以1 帧/5 s的速度连续采集36 帧,通过感兴趣区法扣除肝外影像,经图像放大,取28~32 个动态像素处理,提取肝实质相因子图像,肝动脉灌注相因子图像。结果 13 例HCC动脉灌注因子图像中11 例于占位区呈浓聚像,而正常人和肝血管瘤者未见异常浓聚,诊断效能评价,因子分析法对HCC的诊断灵敏度84.6% ,特异性100% 。结论 因子分析法对HCC的诊断具有较高的灵敏度和特异性,值得推广和应用。
Objective To investigate the qualitative and locational diagnosis of primary hepatocellular carcinoma (HCC) using factor analysis. Methods 16 cases of normal, 13 cases of HCC and 21 cases of hepatic cavernous hemangioma were injected into the 99m Tc eluent 370 MBq (volume < 1 m l) via the elbow vein “projectile” method immediately after 1 frame/5 s. A total of 36 frames were continuously acquired. Extrahepatic images were subtracted by the region of interest method. After image enlargement, 28 to 32 dynamic pixels were processed to extract liver parenchymal factor images and hepatic artery perfusion phase factor images. Results In 13 cases of HCC arterial perfusion factor image, 11 cases showed a thick image in the occupation area, but no abnormal concentration in normal and hepatic hemangioma, diagnostic efficacy evaluation, diagnostic sensitivity of factor analysis method for HCC 84.6% The specificity is 100%. Conclusion The factor analysis method has high sensitivity and specificity for the diagnosis of HCC, and it is worthy of promotion and application.