先锋霉素Ⅱ已证实是一种肾毒性药物,临床上也有逐渐增多的证据表明先锋霉素Ⅰ有时可引起急性肾功能衰竭。本文报导一老年轻度糖尿病伴有尿路感染的患者以常用剂量的先锋霉素Ⅳ治疗,停药后发生短时期肾、肝中毒的情况。患者70岁,男性,因排尿困难,寒战、发热7天入院。患者有轻度糖尿病,15年前作过前列腺癌根除术。此次入院后检查发现脓尿和细菌尿,静脉肾盂造 Pioneermycin II has been shown to be a nephrotoxic drug, and there is also a growing body of evidence that Pioneermycin I can sometimes cause acute renal failure. This article reports a mild diabetic old with urinary tract infection in patients with the usual dose of cephalosporin IV treatment, short-term renal failure occurred after drug withdrawal, liver poisoning. Patient 70 years old, male, admitted to hospital for 7 days due to dysuria, chills and fever. Patients with mild diabetes, made radical prostatectomy 15 years ago. The admission examination found pyuria and bacterial urine, intravenous renal pelvis made