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早在16世纪,Ambroise即发现精索静脉曲张,1880年英国外科医生Barfield首先报道了精索静脉曲张可致不育.精索静脉曲张在男性人群中发病率为10～15%,在男性不育人群中的发病率为35～40%,为男性不育的首要病因.1 治疗方法1.1 药物治疗:1级精索静脉曲张不育症可用药物治疗,2、3级手术后也应配合药物治疗,以改善和提高精子功能,常用药物有:(1)绒毛膜促性腺激素(HCT):(2)克罗米芬及甲基睾丸素;(3)抗精子抗体(AsAb)阳性者,服用抑抗灵;(4)抗菌素、维生素A、维生素E及精氨酸等.1.2 栓塞疗法:精索血管造影时,通过导管行镍钛合金丝血管栓塞器栓塞治疗,随访复发率仅4.8%.也有使用50%葡萄糖行硬化剂栓塞治疗的报告.
As early as the 16th century, Ambroise found varicoceles, British surgeon Barfield first reported infertility varicocele in 1880. The prevalence of varicocele in the male population was 10 to 15% in men is not The incidence of infertility in the population is 35 to 40%, the primary cause of male infertility.1 treatment 1.1 drug treatment: grade 1 varicocele can be treated with drugs, 2,3 after surgery should also be combined with drugs Treatment to improve and enhance sperm function, commonly used drugs are: (1) chorionic gonadotropin (HCT) :( 2) clomiphene and methyl testosterone; (3) anti-sperm antibody (AsAb) (4) antibiotics, vitamin A, vitamin E and arginine, etc .. 1.2 embolization therapy: spermatic cord angiography, catheter nitinol wire embolization embolization, follow-up recurrence rate of only 4.8% Report of 50% glucose sclerotherapy for embolization.