目的 比较 PRK 手术中化学法与机械法去上皮的效果。对象与方法 用前瞻、配对对照对60只 PRK 手术眼分别用化学法或机械法去上皮。观察比较术中情况,术后恢复,随访一年的效果和并发症。结果 两组术后效果,并发症无统计学差异;手术时间化学法显著少于机械法。结论PRK 手术中用化学法去上皮,手术效果和预测性与机械法相同,但较之后者更简便、快捷,安全易操作。 Objective To compare the effect of chemical and mechanical deproteinization on PRK. Subjects and Methods Prospective and paired controls were used to chemically or mechanically remove 60 PRK eyes. Observation and comparison of intraoperative conditions, postoperative recovery, follow-up of one year results and complications. Results The two groups of postoperative effects, complications no significant difference; operation time was significantly less than the mechanical method. Conclusions PRK surgery with chemical removal of the epithelium, surgical results and predictability and mechanical method the same, but more than the latter more simple, fast, safe and easy to operate.