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目的 探讨脑电图 (EEG)及脑地形图 (BEAM )对亚临床肝性脑病 (SHE)诊断及其临床意义。方法 对 32例SHE患者进行EEG、BEAM检测与 30例正常人对照分析 ,并对SHE患者作血氨、血浆白蛋白、空腹血糖检测。结果 SHE组EEG、BEAM异常率为 75 % (2 4/ 32 )与对照组相比 (P <0 .0 1)有非常显著性差异 ,并发现EEG、BEAM异常与血氨升高 ,低血浆白蛋白、低血糖等多种因素有关。结论 SHE患者EEG、BEAM检测异常率明显增高 ,可作为SHE早期诊断的理想方法 ,并对EEG、BEAM异常者可考虑进行降低血氨 ,提高血浆白蛋白及血糖等预防肝性脑病的干预治疗 .
Objective To investigate the clinical value of EEG and BEAM in the diagnosis of subclinical hepatic encephalopathy (SHE). Methods 32 cases of SHE were examined by EEG, BEAM and 30 normal controls. Blood ammonia, plasma albumin and fasting plasma glucose were detected in patients with SHE. Results The abnormal rate of EEG and BEAM in SHE group was significantly higher than that in control group (75%, 24/32) (P <0.01) Albumin, hypoglycemia and other factors. Conclusion The abnormal rates of EEG and BEAM in patients with SHE were significantly higher than those in patients with SHE, which could be used as an ideal method for the early diagnosis of SHE. Interventions to reduce hepatic encephalopathy such as lowering blood ammonia, increasing plasma albumin and blood glucose may be considered in patients with abnormal EEG and BEAM.