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目的分析不同病期支原体肺炎(MPP)患童外周血免疫球蛋白及补体指标表达水平。方法选择2015年1-12月在沈阳市儿童医院门诊就诊或住院治疗MPP患儿24例(MPP组),入选对象分别在急性期和恢复期接受了外周血免疫球蛋白指标(Ig G、Ig A和Ig M)及补体指标(C3和C4)检测,并与同期体检结论健康儿童(对照组)相同测试结果比较。结果 MPP组急性期外周血Ig G、Ig A和Ig M表达强度均明显高于恢复期及对照组,而C3补体水平则明显低于恢复期及对照组(P<0.05),MPP急性期、恢复期C4水平与对照组比较无明显差异(P>0.05)。结论MPP急性期患儿存在明确的免疫球蛋白及补体指标表达失衡。
Objective To analyze the expression of immunoglobulin and complement in peripheral blood of children with mycoplasma pneumoniae (MPP) at different stages. Methods From January to December 2015, 24 children with MPP (MPP group) were enrolled in the outpatient clinic or hospitalized in Shenyang Children’s Hospital. The subjects received the peripheral blood immunoglobulin indexes (Ig G, Ig A and Ig M) and complement markers (C3 and C4), and compared with the same test results of healthy children (control group) in the same period. Results The expression of Ig G, Ig A and Ig M in acute phase of MPP group was significantly higher than that in recovery phase and control group, while the level of C3 complement was significantly lower than that in recovery phase and control group (P <0.05) Recovery C4 level compared with the control group no significant difference (P> 0.05). Conclusion There is an imbalance of immunoglobulin and complement indicators in children with acute MPP.