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目的探讨左氧氟沙星治疗耐多药肺结核的临床疗效。方法选取攀枝花市第四人民医院2012年12月—2013年10月收治的耐多药肺结核患者88例,根据治疗方案不同分为研究组和对照组,每组44例。研究组给予左氧氟沙星治疗,对照组给予常规治疗。比较两组患者治疗3个月和6个月后的痰菌阴转率和X线吸收率。结果治疗3个月和6个月后研究组的痰菌转阴率均高于对照组,X线吸收率高于对照组,差异有统计学意义(P<0.05)。结论左氧氟沙星治疗耐多药肺结核的临床疗效显著。
Objective To investigate the clinical efficacy of levofloxacin in the treatment of multi-drug resistant pulmonary tuberculosis. Methods Eighty-eight MDR-TB patients were selected from the Fourth People’s Hospital of Panzhihua City from December 2012 to October 2013. According to the different treatment plans, they were divided into study group and control group, with 44 cases in each group. The study group was given levofloxacin, while the control group was given routine treatment. The sputum negative conversion rate and X-ray absorption rate were compared between the two groups after treatment for 3 months and 6 months. Results After 3 months and 6 months of treatment, the sputum negative rate of the study group was higher than that of the control group, and the X-ray absorption rate was higher than that of the control group. The difference was statistically significant (P <0.05). Conclusion Levofloxacin is effective in treating multi-drug resistant pulmonary tuberculosis.