百年之前人们发现了肾素,但是关于肾素-血管紧张素系统(RAS)的新认识从未停止过。除了大家公认的作为一种血压和血流量的调节因子之外,它也参与了肾脏的发育过程,而且大量证据证明它参与了心脏和呼吸功能的调节。大多数近期的研究主要集中于RAS的肽产物,以前认为这些物质只是代 Renin was discovered a hundred years ago, but new insights into the renin-angiotensin system (RAS) have never stopped. In addition to its well-established role as a regulator of blood pressure and blood flow, it is also involved in the development of the kidney and there is ample evidence that it participates in the regulation of the heart and respiratory function. Most recent studies have focused mainly on the peptide products of RAS, which were previously thought to be on behalf of