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原发性胆管癌早期诊断困难 ,随着分子生物学的发展 ,已认识到细胞癌变是基因的异常激活或失活所致 ,胆管癌在其发生发展过程中可释放多种肿瘤标志物 ,本文对近年来胆管癌肿瘤标志物的研究进展及其临床意义做一综述
Early diagnosis of primary cholangiocarcinoma is difficult. With the development of molecular biology, it has been recognized that cancerous cells are abnormally activated or inactivated. Cholangiocarcinoma can release a variety of tumor markers during its development. In recent years, the research progress of tumor markers of cholangiocarcinoma and its clinical significance are reviewed