从理论上论证了雌甾化合物的反应活性确系A环,A环中的2号位碳原子和4号位碳原子是活性位置,此处易发生亲电取代反应,生成2位和4位的混合物,可得到2位的单一产物,但无4位单一产物,更无1位产物. Theoretically, it is demonstrated that the reactivity of the estrene is indeed ring A, and the carbon atom at position 2 and the carbon atom at position 4 in the ring A are the active sites where the electrophilic substitution reaction easily occurs to generate the positions 2 and 4 Of the mixture, you can get a single product at 2, but no 4 single product, no more 1 product.