论文部分内容阅读
目的:观察吴氏发泡膏穴位贴敷联合舒利迭吸入防治支气管哮喘的临床疗效。方法:将100例患者随机分成2组各50例,2组按常规予吸入舒利迭,共3月,治疗组在此基础上于三伏天期间予吴氏发泡膏穴位贴敷治疗,观察2组临床疗效、肺功能、抗炎性介质、细胞因子等指标的变化。结果:2组随访1月的临床症状、第1秒用力呼气容积(FEV1)变异率、FEV1占预计值%均有明显改善,2组外周血CD4+、白细胞介素-4(IL-4)水平均较治疗前下降,差异均有显著性意义(P<0.05),但治疗组改善更明显,差异有显著性意义(P<0.05),且随访3月上述情况持续改善,分别与随访1月比较,差异均有显著性意义(P<0.05);而治疗组随访1月外周血CD8+、干扰素-γ(IFN-γ)较治疗前升高,差异有显著性意义(P<0.05),且随访3月后基本稳定,分别与随访1月比较,差异均无显著性意义(P>0.05);对照组治疗前后无明显变化。结论:吴氏发泡膏穴位贴敷联合舒利迭吸入能持续改善哮喘患者症状、肺功能、抗炎性介质,且能调节免疫,有效防治哮喘。
Objective: To observe the clinical efficacy of Wu’s foaming cream acupoint sticking combined with inhalation of seretide to prevent and treat bronchial asthma. Methods: 100 patients were randomly divided into 2 groups of 50 cases, 2 groups were routinely inhaled seretide, a total of 3 months, the treatment group on this basis in the three-day period Wu Wu foaming cream applied to the site, The clinical efficacy, lung function, anti-inflammatory mediators, cytokines and other indexes in 2 groups were changed. Results: The clinical symptoms, the forced expiratory volume in 1 second (FEV 1), and the predicted FEV 1% of 2 groups were significantly improved. The levels of CD4 +, IL-4, (P <0.05), but the treatment group improved more obviously, the difference was significant (P <0.05), and the follow-up of the above conditions continued to improve in March, respectively, and follow-up 1 (P <0.05). The levels of CD8 + and IFN-γ in peripheral blood of patients in the follow-up treatment group were significantly higher than those before treatment (P <0.05), and the differences were significant , And basically stable after 3 months follow-up, respectively, compared with January follow-up, the difference was not significant (P> 0.05); the control group before and after treatment no significant change. Conclusion: Wu foaming cream acupoint application combined with seretide inhalation can continuously improve symptoms, lung function and anti-inflammatory mediators in asthmatic patients, and can regulate immunity and prevent asthma effectively.