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目的探讨幽门螺旋杆菌感染(Hp)与不同亚型脑梗死的相关性,为脑血管病的防治提供依据。方法选取2011年6月至2011年10泰安市中心医院收治的80例急性脑梗死患者,其中大动脉粥样硬化型32例,小动脉闭塞(腔梗)型30例,心源性栓塞型18例,另选取同期健康者60例为对照组,比较各组HpIgG、IgA、IgM阳性率差异。结果大动脉粥样硬化型脑梗死组患者HpIgG阳性率显著高于对照组,差异有统计学意义(P<0.05)。结论 Hp感染与动脉粥样硬化密切相关,可能是通过加重动脉粥样硬化的发生、发展,导致脑梗死的发生。
Objective To investigate the correlation between Helicobacter pylori infection (Hp) and different subtypes of cerebral infarction and provide evidence for the prevention and treatment of cerebrovascular disease. Methods Eighty patients with acute cerebral infarction who were treated in Central Hospital of Tai’an from June 2011 to 2011 were enrolled. Among them, there were 32 cases of large atherosclerosis, 30 cases of arteriole occlusion (CA) and 18 cases of cardioembolism , Another 60 cases of healthy people in the same period were selected as the control group, and the positive rates of HpIgG, IgA and IgM in each group were compared. Results The positive rate of HpIgG in patients with atherosclerotic cerebral infarction was significantly higher than that in the control group (P <0.05). Conclusion Hp infection is closely related to atherosclerosis, which may be caused by the occurrence and development of atherosclerosis, leading to cerebral infarction.