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Ⅲ型变态反应此型变态反应称免疫复合物型,又称血管炎型变态反应。在正常状态下,免疫复合物在体内的形成是一种生理性的防御性机能,形成的复合物易被吞噬消除。但在某种按特定条件下,如形成的免疫复合物不易被清除,则可在局部沉积,激活补体,,吸引中性粒细胞集聚,从而引起一系列组织损伤,即为免疫复合物病。 (一)免疫复合物致病的条件:免疫复合物能否致病取决于免疫复合物颗粒的大小及其是否能沉着于机体一定部位。 1、免疫复合物的性能:免疫复合物是抗原与抗体结合的集团,其颗粒的大小与抗原、抗体两者
Type III allergy This type of allergy called immune complex type, also known as vasculitic allergy. Under normal conditions, the formation of immune complexes in the body is a physiological defensive function, the complex formed easily swallowed to eliminate. However, under certain conditions, if the formed immune complexes are not easily removed, the local deposition and activation of complement may attract agglutination of neutrophils and cause a series of tissue damage, namely immune complex diseases. (A) the immune complex pathogenic conditions: whether the immune complex pathogenesis depends on the size of the immune complex particles and whether it can be deposited in a certain part of the body. 1, the performance of immune complexes: immune complexes are antigen and antibody binding group, the size of the particles and antigen, both antibodies