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Long noncoding RNA H19 inhibits the proliferation of fetal liver cells and the Wnt signaling pathway
[会议论文] 作者:王少冰;袁继行;杨富;刘岩;周传传;刘峰;马金召;孙树汉;王芳;,
来源:第十四次全国医学遗传学学术会议 年份:2015
Long noncoding RNA (IncRNA) H19 is the first imprinted IncRNA to be defined.H19 has been implicated in the development of the liver, as H19 is the most diff...
Gender related long non-coding RNA FTX transcribed by X chromosome inhibits hepatocellular carcinoma
[会议论文] 作者:刘峰, 袁继行, 杨富, 马金召, 王田田, 周传传, 余建,,
来源:第十四次全国医学遗传学学术会议论文汇编 年份:2015
As long been known,males are more susceptible to hepatocellular carcinoma(HCC)than females,but the reason still remains elusive.In this study,we found that long noncoding RNA five prime to Xist(Inc-FT...
Gender related long non-coding RNA FTX transcribed by X chromosome inhibits hepatocellular carcinoma
[会议论文] 作者:刘峰,袁继行,杨富,马金召,王田田,周传传,余建,周伟平,王芳,孙树汉,
来源:第十四次全国医学遗传学学术会议 年份:2015
As long been known, males are more susceptible to hepatocellular carcinoma(HCC) than females, but the reason still remains elusive.In this study, we found that long non-coding RNA five prime to Xist (...
[期刊论文] 作者:毕峰瑞,周传传,袁继行,孙树汉,,
来源:第二军医大学学报 年份:2016
目的观察和比较在人肝癌与癌旁组织中蛋白磷酸酶1调节亚基16A(protein phosphatase 1regulatory subunit 16A,PPP1R16A)基因在基因组和转录水平的差异,探讨靶向沉默PPP1R16A...
[会议论文] 作者:赵子夜, 刘岩, 王少冰, 袁继行, 杨富, 王芳,,
来源: 年份:2004
目的筛选胚胎期肝脏和肝癌中均高表达的蛋白编码基因,并研究其对肝癌发生、转移的调控机制。方法应用表达谱芯片筛选出在胚胎期和肝癌组织中均高表达的编码基因,经过表达、干...
Identification of copy number variations associated lncRNAs analysis reveals lncRNA-PRAL promotes ap
[会议论文] 作者:周传传,杨富,孙树汉,
来源:2014全球华人遗传学大会暨全国第十三次医学遗传学学术会议 年份:2014
Recurrent genome copy number aberrations are known to be a common feature of many cancers,including Hepatocellular carcinoma (HCC), and their analysis is expected to reveal genes involved in carcinoge...
The Histone Deacetylase4/Sp1/miR-200a Regulatory Network Contributes to Aberrant Histone Acetylation
[会议论文] 作者:袁继行;杨富;王芳;孙树汉;,
来源:中华医学会2012年医学遗传学年会暨全国第十一次医学遗传学学术会议 年份:2012
As an important epigenetic mechanism,histone acetylation modulates the transcription of many genes and plays important roles in hepatocellular carcinoma(HCC...
[会议论文] 作者:袁继行,杨富,王芳,孙树汉,
来源:2012遗传学进步促进粮食安全与人口健康高峰论坛 年份:2012
Hepatocellular carcinoma (HCC) is the fifth most common cancer in the world and is a leading cause of cancer death.However,the pathophysiological mechanisms...
The Histone Deacetylase4/Sp1/miR-200a Regulatory Network Contributes to Aberrant Histone Acetylation
[会议论文] 作者:袁继行,杨富,王芳,孙树汉,
来源:中华医学会2012年医学遗传学年会暨全国第十一次医学遗传学学术会议 年份:2012
As an important epigenetic mechanism,histone acetylation modulates the transcription of many genes and plays important roles in hepatocellular carcinoma(HCC).Aberrations in histone acetylation have be...
[会议论文] 作者:袁继行, 杨富, 王芳, 孙树汉,
来源:遗传学进步促进粮食安全与人口健康高峰论坛论文集 年份:2012
...
LncRNA-LALR accelerates hepatocyte proliferation and cell cycle progression in liver regeneration by
[会议论文] 作者:徐丹,杨富,毕海姗,张铃,周传传,袁继行,刘峰,王芳,孙树汉,
来源:中华医学会2012年医学遗传学年会暨全国第十一次医学遗传学学术会议 年份:2012
...
LncRNA-LALR accelerates hepatocyte proliferation and cell cycle progression in liver regeneration by
[会议论文] 作者:徐丹,杨富,毕海姗,张铃,周传传,袁继行,刘峰,王芳,孙树汉,
来源:中华医学会2012年医学遗传学年会暨全国第十一次医学遗传学学术会议 年份:2012
...
[会议论文] 作者:刘峰,袁继行,孙树汉,
来源:2014全球华人遗传学大会暨全国第十三次医学遗传学学术会议 年份:2014
肝细胞肝癌是非常多发的消化系统肿瘤,发病率以东亚地区包括我国最高,肝癌的预后较差,病死率高,五年生存率极低.肝癌的发病存在明显的性别差异,有些地区男女比甚至高达4:1.多年以来关于肝癌发病的性别差异已有很多研究,但是均未能完全解释其机制.我们实验室进行......
Gender Disparity of UBE2D1 Copy Number Variations Driven by Continuous IL-6 Microenvironment in Hepa
[会议论文] 作者:周传传,毕锋瑞,袁继行,王芳,杨富,马金召,袁声贤,陶其飞,刘峰,王田田,周伟平,孙树汉,
来源:第十四次全国医学遗传学学术会议 年份:2015
The exact mechanisms of gender disparity in hepatocellular carcinoma (HCC) are largely unknown.Reanalysis of large-scale genomic profiles lead us to explore the gender differences from copy number var...
[会议论文] 作者:马金召, 杨富, 孙树汉,,
来源: 年份:2004
近年来,RNA水平的表观遗传修饰因其重要的病理生理功能越来越受到研究人员的重视。其中RNA的甲基化(m6A,N6-methyl-adenosine)修饰作为转录后修饰的一种成为最重要的研究靶点...
[期刊论文] 作者:袁继行, 王芳, 孙树汉,,
来源:医学研究与教育 年份:2016
目的探讨案例教学法(CBL)、问题驱动教学法(PBL)在临床遗传学教学中的应用效果。方法选取第二军医大学2013级临床医学五年制专业60名学生作为研究对象,按教学方法不同分为2组...
Gender related long non-coding RNA FTX transcribed by X chromosome inhibits hepatocellular carcinoma
[会议论文] 作者:刘峰[1]袁继行[1]杨富[1]马金召[1]王田田[1]周传传[1]余建[2]周伟平[2]王芳[1]孙树汉[1],
来源:第十四次全国医学遗传学学术会议 年份:2015
As long been known, males are more susceptible to hepatocellular carcinoma(HCC) than females, but the reason still remains elusive.In this study, we found t...
[会议论文] 作者:刘峰,杨富,王芳,孙树汉,
来源:第十二次全国医学遗传学学术会议 年份:2013
目的 肝癌是世界第6大肿瘤,同时在肿瘤导致的死亡中排第3位.男性肝癌患病率明显高于女性,尽管已有很多相关研究,但其具体原因仍不清楚.方法和结果 我们利用第二代测序技术,对3例男性肝癌患者肿瘤组织与癌旁组织进行转录组测序.我们发现Y染色体上假基因编码的长......
Identification of copy number variations associated lncRNAs analysis reveals IncRNA-PRAL promotes ap
[会议论文] 作者:周传传,王芳,孙树汉,杨富,徐丹,张铃,袁继行,袁声贤,毕海珊,陶其飞,刘峰,
来源:中华医学会2012年医学遗传学年会暨全国第十一次医学遗传学学术会议 年份:2012
Recurrent genome copy number aberrations are known to be a common feature of many cancers,including hepatocellular carcinoma(HCC),and their analysis is expected to reveal genes involved in carcinogene...
[会议论文] 作者:毕海珊,袁继行,杨富,王芳,孙树汉,
来源:第十二次全国医学遗传学学术会议 年份:2013
Background & Aims: H19 is one of the earliest identified and studied long noncoding RNAs.It is presumed that H 19 is essential for regulating development and disease conditions, and is associated with...
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