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,ONO-1078 reduces NMDA-induced brain injury and vascular cell adhesion molecule-1 expression in rats
[期刊论文] 作者：Li-hui ZHANG,Er-qing WEI,
来源：中国药理学报（英文版） 年份：2005
Aim: To determine whether ONO-1078 (pranlukast), a potent cysteinyl leukotriene receptor 1 (CysLT1) antagonist, has an effect on N-methyl-D-aspartate (NMDA)indu...
[期刊论文] 作者：Dan-Na Shen,Li-Hui Zhang,Er-Qing Wei,Yi Yang,,
来源：Neuroscience Bulletin 年份：2015
In the nervous system, neurons contact each other to form neuronal circuits and drive behavior, relying heavily on synaptic connections. The proper development...
Neuropotective effect of HAMI3379,a selective cysteinyl leukotriene receptor 2 antagonist,on focal c
[会议论文] 作者：Qiao-Juan Shi,Li Xiao,Xiao-Ying Sa,Er-Qing Wei,
来源：第十届中国实验动物科学年会 年份：2012
Objective Cysteinyl leukotrienes(CysLTs)induce inflammatory responses mediated by activating CysLT1 and CysLT2 receptor.We have recently reported CysLT2 receptor is involved in neuron injury,astrocyto...
,Cysteinyl leukotriene receptor 1 is involved in /N-methyl-D-aspartate-mediated neuronal injury in m
[期刊论文] 作者：Qian DING,Er-qing WEI,Yan-jun ZHANG,Wei-ping ZHANG,Zhong CHEN,
来源：中国药理学报（英文版） 年份：2006
Aim: To determine whether cysteinyl leukotriene receptor 1 (CysLT1 receptor) is involved in N-methyl-D-aspartate (NMDA)-induced excitotoxic injury in the mouse...
,Montelukast modulates lung CysLT1 receptor expression and eosinophilic inflammation in asthmatic mi
[期刊论文] 作者：Yan-jun ZHANG,Lei ZHANG,Shao-bin WANG,Hua-hao SHEN,Er-qing WEI,
来源：中国药理学报（英文版） 年份：2004
AIM: To determine the expressions of cysteinyl leukotriene receptors, CysLT1 and CysLT2, in airway eosinophilic inflammation of OVA-induced asthmatic mice and t...
[会议论文] 作者：Cheng-Tan LI,Wei-Ping ZHANG,Yue-Mei YUAN,San-Hua FANG,Er-Qing WEI,
来源：中国神经科学学会第四次会员代表大会暨第七届全国学术会议(The 7th Biennial Meeting and the 年份：2007
5-Lipoxygenase (5-LOX) is the key enzyme metabolizing arachidonic acid to produce pro-inflammatory leukotrienes.The initial step of 5-LOX activation is its translocation to the nuclear envelope.In cul...
,Nuclear translocation of cysteinyl leukotriene receptor 1 is involved in oxygen-glucose deprivation
[期刊论文] 作者：San-hua FANG,Ka-na LIN,Xue-qin HUANG,Yun-bi LU,Wei-ping ZHANG,Er-qing WEI,
来源：中国药理学报（英文版） 年份：2012
...
Inhibitory effect of caffeic acid on activation of 5-1ipoxygenase induced by oxidative stress in PCI
[会议论文] 作者：Cheng-tan Li,Li-hui Zhang,Jian-bo Zhao,Shane-hua Fang,Wei-ping Zhang,Er-qing Wei,
来源：国际药理学术研讨会暨第三届两岸三地药理学学术会议 年份：2010
...
Involvement of 5-lipoxygenase/cysteinyl leukotriene receptor 1 in rotenone-and MPP+-induced BV2 micr
[会议论文] 作者：Yan-Fang Wang,Xiao-yan Zhang,Cheng-tan Li,Jian-bo Zhao,Er-qing Wei,Li-hui Zhang,
来源：Iternational Frontiers Symposium foe Neuron & Disease(国际神经与疾 年份：2012
Neuroinflammation plays a prominent role in the pathogenesis of Parkinsons disease (PD), and microglial activation contributes to initiating and maintaining brain inflammation and neuronal death.5-Lip...
Cysteinyl leukotriene receptor 1 and 2 are involved in astrocyte proliferation or injury following o
[会议论文] 作者：Xiao-Jia HUANG,Wei-Ping ZHANG,Cheng-Tan LI,San-Hua FANG,Yun-Bi LU,Er-Qing WEI,
来源：中国神经科学学会第四次会员代表大会暨第七届全国学术会议(The 7th Biennial Meeting and the 年份：2007
Cysteinyl leukotrienes (CysLTs) are 5-1ipoxygenase (5-LOX) metabolites of arachidonic acid and exert potent pro-inflammatary effects via their receptors including cysteinyl leukotriene receptors 1 and...
Extracellular signal-regulated kinase pathways may mediated the protective effect of electrical stim
[会议论文] 作者：Yong-Mei ZHANG,Er-Qing WEI,Li LI,Wei-Li QIAO,Lin WANG,Jian-Fu ZHANG,
来源：中国神经科学学会第四次会员代表大会暨第七届全国学术会议(The 7th Biennial Meeting and the 年份：2007
Objective To elucidate the role of the extracellular signal-regulated kinase (ERK) pathway in mediating the effects of electrical stimulation of the paraventricular nucleus (PVN) on apoptosis and prol...
,Pranlukast reduces neutrophil but not macrophage/microglial accumulation in brain after focal cereb
[期刊论文] 作者：Li-sheng CHU,Er-qing WEI,Guo-liang YU,San-hua FANG,Yu ZHOU,Meng-ling WANG,Wei-ping ZHANG,
来源：中国药理学报（英文版） 年份：2006
Aim:To determine whether pranlukast.a cysteinyl leukotriene receptor-1 antagonist,exerts an anti-inflammatory effect on focal cerebral ischemia in mice.Methods:...
,Minocycline inhibits 5-lipoxygenase activation and brain inflammation after focal cerebral ischemia
[期刊论文] 作者：Li-sheng CHU,San-hua FANG,Yu ZHOU,Guo-hang YU,Meng-ling WANG,Wei-ping ZHANG,Er-qing WEI,
来源：中国药理学报（英文版） 年份：2007
Aim: To determine whether the anti-inflanunatory effect of minocycline on postis-chemic brain injury is mediated by the inhibition of 5-lipoxygenase (5-LOX) exp...
[期刊论文] 作者：Qian DING,San-hua FANG,Yu ZHOU,Li-hui ZHANG,Wei-ping ZHANG,Zhong CHEN,Er-qing WEI,
来源：中国药理学报（英文版） 年份：2007
Aim: To determine whether the cysteinyl leukotriene receptor 1 (CysLT1 receptor) modulates brain cryoinjury and whether the CysLT1 receptor antagonist pranlukas...
,Monosialoganglioside protected ischemic rat hippocampal slices through stabilizing expression of N-
[期刊论文] 作者：Jian-ren LIU,Mei-ping DING,Er-qing WEI,Jian-zheng HUANG,Ying SONG,Qiang DING,Qiu-fu GE,
来源：中国药理学报（英文版） 年份：2004
AIM: To determine direct protective effect of monosialoganglioside (GM1) on hippocampal slices after oxygenglucose deprivation and reperfusion (OGD/RP), and inv...
[期刊论文] 作者：Yu ZHOU,San-hua FANG,Yi-lu YE,Li-sheng CHU,Wei-ping ZHANG,Meng-ling WANG,Er-qing WEI,
来源：中国药理学报（英文版） 年份：2006
Aim: To investigate the effects of caffeic acid on early and delayed injuries after focal cerebral ischemia in rats, and the possible relation to 5-lipoxygenase...
,Histamine ameliorates spatial memory deficits induced by MK-801 infusion into ventral hippocampus a
[期刊论文] 作者：Li-sha XU,Li-xia YANG,Wei-wei HU,Xiao YU,Li MA,Lu-ying LIU,Er-qing WEI,Zhong CHEN,
来源：中国药理学报(英文版) 年份：2005
Aim: To investigate the role of histamine in memory deficits induced by MK-801 infusion into the ventral hippocampus in rats. Methods: An 8-arm radial maze (4ar...
,Cysteinyl leukotriene receptors CysLT1 and CysLT2 are upregulated in acute neuronal injury after fo
[期刊论文] 作者：Yan-jun ZHANG,Lei ZHANG,Yi-lu YE,San-hua FANG,Yu ZHOU,Wei-ping ZHANG,Yun-bi LU,Er-qing WEI,
来源：中国药理学报（英文版） 年份：2006
Aim: To determine whether cysteinyl leukotriene receptors (CysLT1 and CysLT2) are upregulated in acute neuronal injury after focal cerebral ischemia in mice, an...
[期刊论文] 作者：Ying-xia GONG,Min LV,Yong-ping ZHU,Yuan-yuan ZHU,Er-qing WEI,Hong SHI,Qun-li ZENG,Zhong CHEN,
来源：中国药理学报（英文版） 年份：2007
Aim:The conditioned place preference (CPP) paradigm was used to investigate the effects of endogenous histamine on the processes leading to morphine-induced rew...
,Baicalin attenuates oxygen-glucose deprivation-induced injury by inhibiting oxidative stress-mediat
[期刊论文] 作者：LI,Wei-ping ZHANG,San-hua FANG,Yun-bi LU,Li-hui ZHANG,Ling-ling QI,Xue-qin HUANG,Xiao-jia HUANG,Er-qing WEI,
来源：中国药理学报(英文版) 年份：2010
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