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Mutation and β-adrenergic Stimulation Synergistically Sensitize Ryanodine Receptors in Intact Cardio
[会议论文] 作者：Yun-Bo Guo,Hua-Qian Yang,Shi-Qiang Wang,
来源：第十三次中国生物物理学术大会 年份：2013
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CPVT-related mutation increased RyR2 channel sensitivity to calcium influx through L-type calcium ch
[会议论文] 作者：Yun-Bo Guo,Hua-Qian Yang,Jing-Chao Li,Shi-Qiang Wang,
来源：International Conference for Physiological Sciences 2012(201 年份：2012
Catecholaminergic polymorphic ventricular tachycardia (CPVT) is an arrhythmogenic cardiomyopathy that manifests as recurrent syncope and sudden cardiac death triggered by high adrenergic tone.Mutation...
β2-adrenergic Signaling Modulates Excitation-contraction Coupling without Sensitizting Ryanodine Rec
[会议论文] 作者：Peng Zhou,Hua-qian Yang,Yan-Ting Zhao,Ying-Ying Hu,Shu-Hua Bai,Xue-Mei Hao,Shi-Qiang Wang,
来源：中国生理学会第24届全国会员代表大会暨生理学学术大会 年份：2014
β-Adrenergic receptor (βAR),mainly β1AR,mediates positive inotropy in heart.However,since β1AR induces severe arrhythmia in failing heart,it can not be used for clinical treatment.β2-adrenergic recept...
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