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[期刊论文] 作者：Ting BAI,Yong YANG,Ji-xing NAN,
来源：中国药理学与毒理学杂志 年份：2017
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[期刊论文] 作者：Yong YANG,Ting BAI,Ji-xing NAN,
来源：中国药理学与毒理学杂志 年份：2017
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Studies on the mechanism of SIRT1/AMPK signaling pathway between hepatocytes and hepatic stellate ce
[期刊论文] 作者：Ting BAI,Yong YANG,Ji-xing NAN,Qing-gao ZHANG,,
来源：中国药理学与毒理学杂志 年份：2017
OBJECTIVE To investigate the mechanism of SIRT1/AMPK signaling pathway between hepatocytes and hepatic stellate cells(HSCs).METHODS Normal human Chang liver cel...
Hepato-protective effect of thymoquinone against acetaminophen induced liver injury is associated wi
[期刊论文] 作者：Yong YANG,Ting BAI,Ji-xing NAN,Qing-gao ZHANG,,
来源：中国药理学与毒理学杂志 年份：2017
OBJECTIVE To investigate the hepato-protective mechanism of thymoquinone(TQ) on the development of acetaminophen(APAP)-induced liver injury.METHODS In vivo,male...
Tetrandrine stimulates the apoptosis of hepatic stellate cells and ameliorates development of fibros
[期刊论文] 作者：Ming-Fu Yin,Li-Hua Lian,Dong-Ming Piao,Ji-Xing Nan,
来源：世界胃肠病学杂志（英文版） 年份：2007
AIM: To investigate the therapeutic effect of tetrandrine on liver fibrosis induced by thioacetamide in rats in vivo and in vitro.METHODS: In vitro study: we in...
Cucurbitacin E induces apoptosis and attenuates activation of hepatic stellate cells via PI_3K/Akt-A
[期刊论文] 作者：You-li YAO,Li-hua LIAN,Shuang JIANG,Ji-xing NAN,Yan-ling WU,,
来源：中国药理学与毒理学杂志 年份：2015
OBJECTIVE Hepatic fibrosis is a wound-healing response for injury.Activated hepatic stellate cells(HSCs)are the preferred targets of anti-hepatic fibrotic thera...
Gentiana manshurica Kitagawa prevents acetaminopheninduced acute hepatic injury in mice via inhibiti
[期刊论文] 作者：Ai-Yan Wang,Li-Hua Lian,Ying-Zi Jiang,Yan-Ling Wu,Ji-Xing Nan,
来源：世界胃肠病学杂志（英文版） 年份：2010
AIM: To investigate the in vivo hepatoprotective effects and mechanisms of Gentiana manshurica Kitagawa (GM) in acetaminophen (APAP)-induced liver injury in mic...
Endotoxin-and D-galactosamine-induced fulminant hepatic failure improved by the administration of cr
[会议论文] 作者：Li-Hua LIAN,Quan JIN,Yan-Ling WU,Ting BAI,Ji-Xing NAN,
来源：第二届世界天然药物和传统药物药理学学术会议 年份：2012
AIM Cryptotanshinone (CTN), one of the major constituents of tanshinones, was investigated for hepatoprotective effects in D-galactosamine (D-GalN)/lipopolysaccharide (LPS)-induced fulminant hepatic f...
P2X7 receptor inhibitor suppressed extracellular ATP/LPS-primed human hepatic stellate cells activat
[期刊论文] 作者：Shuang JIANG,Quan JIN,Yan-ling WU,You-li YAO,Ji-xing NAN,Li-hua LIAN,,
来源：中国药理学与毒理学杂志 年份：2015
OBJECTIVE To investigate the effect of P2X7receptor(P2X7r)inhibition,using a specific inhibitor(A438079)to prevent the development of liver fibrosis on human he...
[会议论文] 作者：Li-hua LIAN,Yan-ling WU,Ting BAI,Shuang JIANG,Yong YANG,Ji-xing NAN,
来源：The 12th Meeting of the Asia Pacific Federation of Pharmacol 年份：2013
Aim: Gentiopicroside-containing extract and gentiopicroside from Gentiana manshurica Kitagawa (GM) was investigated for their hepatoprotective effects in vivo.Methods: We applied in vivo model of acet...
[会议论文] 作者：Ting BAI,Ji-xing NAN,Yong YANG,Li-hua LIAN,Yan-ling WU,Shuang JIANG,Hui-xing ZHENG,Xin LI,Jin-bin LI,,
来源：The 12th Meeting of the Asia Pacific Federation of Pharmacol 年份：2013
Aim: Thymoquinone (TQ) is the main active ingredient from the seeds of Nigella sativa Linn, which has been traditionally used in the Middle East and Southeast Asian countries to treat ailments includi...
[会议论文] 作者：Yong YANG,Ji-xing NAN,Ting BAi,Li-hua LIAN,Yan-ling WU,Shuang JIANG,Hui-xing ZHENG,Xin LI,Jin-bin LI,,
来源：The 12th Meeting of the Asia Pacific Federation of Pharmacol 年份：2013
Aim: Liver Kinase B1 (LKB1) proteins serve as a master regulator of metabolismthat inhibits anabolic processes and stimulates catabolic processes.In the present study, we investigated the roles of LKB...
[会议论文] 作者：Shuang JIANG,Ji-xing NAN,Li-hua LIAN,Yan-ling WU,Ting BAI,Yong YANG,Xin LI,You-li YAO,Jin-bin LI,Hui-xing,
来源：The 12th Meeting of the Asia Pacific Federation of Pharmacol 年份：2013
Aim: The ATP-gated P2X7 receptor (P2X7r) is a promising therapeutic target in chronic inflammatory diseases including liver fibrosis.The underlying molecular mechanisms remain to be elucidated.Methods...
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