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Activation of unfolded protein response overcomes Ibrutinib resistance in diffuse large B-cell lymph
[期刊论文] 作者：Xiao-tuan Zhang,Xiao-bei Hu,Han-lin Wang,Wei-juan Kan,Lei Xu,Zhi-jia Wang,Yu-qi Xiang,Wen-biao Wu,Bo,
来源：中国药理学报（英文版） 年份：2021
Diffuse large B-cell lymphoma (DLBCL) is the most widespread type of non-Hodgkin lymphoma (NHL).As the most aggressive form of the DLBCL,the activated B-cell-li...
Downregulation of c-Myc expression confers sensitivity to CHK1 inhibitors in hematologic malignancie
[期刊论文] 作者：Kai-long Jiang,Le-xian Tong,Tao Wang,Han-lin Wang,Xiao-bei Hu,Gao-ya Xu,Ting-ting Jin,Wei-juan Kan,Lei,
来源：中国药理学报（英文版） 年份：2022
Checkpoint kinase 1 inhibitors(CHK1 i)have shown impressive single-agent efficacy in treatment of certain tumors,as monotherapy or potentiators of chemotherapy in clinical trials,but the sensitive tumor types and downstream effectors to dic......
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