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[会议论文] 作者:Yan Li,Xun Li,Wenge Zhong,Renxiao Wang,
来源:中国化学会第14 届全国计算(机)化学学术会议暨分子模拟国际论坛 年份:2017
G protein-coupled receptors(GPCRs)are still the largest target class in current drug discovery.Since 2007,with the great technology breakthroughs in GPCR crystallography,~150 GPCR complex structures h...
[期刊论文] 作者:Honglei Ma,Wei Huang,Xiaoxi Wang,Lihua Zhao,Yi Jiang,Feng Liu,Wei Guo,Xianqiang Sun,Wenge Zhong,Daopenq,
来源:细胞研究(英文版) 年份:2020
Dear Editor,rnThe glucagon-like peptide-1 receptor(GLP-1R)belongs to class B G protein-coupled receptors(GPCRs).It is a clinically proven target for type 2 diab...
Preclinical evaluation of AMG 337, a highly selective small molecule MET inhibitor, in hepatocellula
[会议论文] 作者:Zhiqiang Du,Sean Caenepeel,Yuqing Shen,Karen Rex,Yanni Zhang,En-tzu Tang,Ouhong Wang,Wenge Zhong,Hui,
来源:第十八届全国临床肿瘤学大会暨2015年CSCO学术年会 年份:2015
Objective: Hepatocellular carcinoma (HCC) is the third leading cause of cancer-related deaths worldwide.Aberrant hepatocyte growth factor/MET signaling has been implicated in hepatocarcinogenesis, sug...
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