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[期刊论文] 作者：JIANG Hang-yu,LI Yu-qi,XIANG Xiao-cong,TANG Zhi-li,LIU Kang,SU Qiang,ZHANG Xiao-fen,LI Lin,
来源：中国药理学与毒理学杂志 年份：2021
Chaetocin is a natural metabolite product with various biological activities and pharmacological functions isolated from Chaetomium species fungi belonging to the thiodiketopyrazines.Numerous studies have demonstrated a wide range of antitu......
Activation of unfolded protein response overcomes Ibrutinib resistance in diffuse large B-cell lymph
[期刊论文] 作者：Xiao-tuan Zhang,Xiao-bei Hu,Han-lin Wang,Wei-juan Kan,Lei Xu,Zhi-jia Wang,Yu-qi Xiang,Wen-biao Wu,Bo,
来源：中国药理学报（英文版） 年份：2021
Diffuse large B-cell lymphoma (DLBCL) is the most widespread type of non-Hodgkin lymphoma (NHL).As the most aggressive form of the DLBCL,the activated B-cell-li...
Downregulation of c-Myc expression confers sensitivity to CHK1 inhibitors in hematologic malignancie
[期刊论文] 作者：Wei-juan Kan,Lei Xu,Jia-nan Li,Kai-xiang Zhang,Ning Song,Jie-yu Liu,Meng-meng Zhang,Wen-biao Wu,Yu-qi Xiang,
来源：中国药理学报（英文版） 年份：2022
Checkpoint kinase 1 inhibitors(CHK1 i)have shown impressive single-agent efficacy in treatment of certain tumors,as monotherapy or potentiators of chemotherapy in clinical trials,but the sensitive tumor types and downstream effectors to dic......
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