β-cells相关论文
阿必鲁泰皮下注射剂是一种长效胰高血糖素样肽-1(GLP-1)受体激动剂,每周皮下注射1次,主要结合饮食与运动用于改善2型糖尿病患者的......
Aim: To investigate the activity and expression of neutral ceramidase (N-CDase) in the insulin-secreting cell line INS-1......
,W2476 ameliorates β-cell dysfunction and exerts therapeutic effects in mouse models of diabetes via
Recent evidence shows that high glucose levels recruit carbohydrate response element-binding protein,which binds the pro......
,The zinc transporter Slc39a5 controls glucose sensing and insulin secretion in pancreatic β-cells v
Zinc levels are high in pancreatic β-cells,and zinc is involved in the synthesis,processing and secretion of insulin in......
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
目的研究大明胶囊(Daming capsule,DM)对链脲佐菌素(streptozocin,STZ)诱导的1型糖尿病大鼠的血糖影响。方法将65只成年雄性Spragu......
目的研究胰岛β细胞损伤后胰岛再生过程中Wnt/β-catenin信号通路的生物调控。方法 STZ破坏新生大鼠胰岛β细胞,免疫组织化学观察1......
Roux-en-Y gastric bypass promotes expression of PDX-1 and regeneration of β-cells in Goto-Kakizaki r
AIM: To study the effects of Roux-en-Y gastric bypass (RYGB) on the expression of pancreatic duodenal homeobox- 1 (PDX-1......
目的：探讨人α1-抗胰蛋白酶（hAAT）蛋白在胰岛β细胞移植中的免疫抑制和保护作用。方法：构建稳定表达hAAT蛋白的NIT-hAAT细胞系。将NIT-......
<正> Liver X receptors(LXRs)are members of the nuclear receptor superfamily,which have been implicated in lipid ho-meost......
目的研究大明胶囊（Daming capsule，DM）对链脲佐菌素（streptozocin，STZ）诱导的1型糖尿病大鼠的血糖影响。方法将65只成年雄性Sprague－Dawle......
脂肪因子包括脂肪细胞分泌的多种活性因子，它们通过内分泌方式调节胰岛β细胞的胰岛素分泌、基因表达以及细胞凋亡等多方面的功能。......
Type 1 diabetes mellitus is an autoimmune disease,which results in the permanent destruction of β-cells of the pancreat......
转录因子FoxO1是叉头家族O的亚族成员之一,是胰岛素/胰岛素样生长因子信号通路中的关键分子。FoxO1蛋白主要有磷酸化、乙酰化和泛......
Cyclic nucleotide phosphodiesterase 3B is connected to osteopontin and protein kinase CK2 in pancrea
Islets from RIP-PDE3B mice, exhibiting β-cell specific overexpression of the cAMP/cGMP-degrading enzyme phosphodiestera......
Alperujo, an antioxidant-rich by-product of olive oil extraction, could protect β-cells against oxidative damage. Our g......
Aim: To identify the influence of pancreatic stellate cell (PSCs) secretions on gene expression profiles of Min6 cells b......
Type 2 diabetes is one of the most prevalent and serious metabolic diseases.Under diabetic conditions,chronic hyperglyce......
The pancreas became one of the first objects of regenerative medicine,since other possibilities of dealing with the panc......
Chronic alcohol consumption potentiates the development of diabetes through pancreatic β-cell dysfun
Chronic ethanol consumption is well established as a major risk factor for type-2 diabetes(T2D), which is evidenced by i......
