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Dopamine (DA) has been reported to involve in the regulation of insulin secretion of pancreatic islets and protection of......
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Total pancreatectomy with islet autotransplantation in diabetic and pre-diabetic patients with intra
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通过向ICR小鼠胆总管注射胶原酶V的方法体外分离胰岛,并从中分离培养出nestin+细胞,之后通过低糖、低血清诱导其分化产生类胰岛样细胞......
AIM:To explore the effects of fentanyl on insulin release from freshly isolated rat pancreatic islets in static culture.......
目的研究在非β细胞中表达成熟胰岛素,探索替代胰岛素注射或胰岛移植治疗1型糖尿病的方法 .方法采用重叠区扩增基因拼接法(gene sp......
目的 :观察实验性糖尿病大鼠腹腔内移植海藻酸钠微囊化成猪胰岛治疗效果.方法 :以海藻酸钠一多聚赖氨酸作为制备微囊的材料 ,将 18......
目的胰岛的纯度和活性对胰岛移植治疗糖尿病的疗效有很大影响。探讨一种大鼠胰岛分离纯化的新方法,以获得高纯度、高产量、活性好......
Retinoids (vitamin A and its natural and synthetic analogs) are required by most tissues for maintaining the normal heal......
Study of the immunoisolating effects of barium-alginate microencapsulation on rat islets allograft s
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
目的 观察辛伐他汀对大鼠胰岛β细胞葡萄糖刺激的胰岛素分泌(GSIS)的抑制作用及其机制.方法 8周龄健康雄性Wistar大鼠60只,体重250......
对 91例Ⅱ型糖尿病患者及 2 8例正常人的血清 ,用ELLSA法测定谷氨酸脱羧酶抗体(GAD Ab)及胰岛细胞抗体 (ICA)。结果 :Ⅱ型糖尿病人......
Study of the immunoisolating effects of barium-alginate microencapsulation on rat islets allograft s
Objective: To evaluate the immunoisolating effects of barium-alginate microencapsulation on islets allograft survival. M......
目的 评估具有代谢综合征高危因素人群胰岛β细胞分泌功能及胰岛素抵抗情况,为早期预防提供参考依据.方法 2012年3月-2013年3月收......
对91例Ⅱ型糖尿病患者及28例正常人的血清,用ELLSA法测定谷氨酸脱羧酶抗体(GAD-Ab)及胰岛细胞抗体(ICA)。结果:Ⅱ型糖尿病人中抗体阳性率为30.76%,GAD-Ab阳性为17.50%,ICA阳性为15.38%,双抗......
文章提出了一种可解决带岛区约束数据域的三角剖分通用算法,通过对岛区制图边界拓扑结构建立与分析,引入双联点和辅助约束边界概念......
目的评价Dextran不连续密度梯度离心法纯化大鼠胰岛的效果.方法采用V型胶原酶分离出大鼠胰岛,并应用Dextran不连续密度梯度离心法......
目的比较6种常见2型糖尿病动物模型的生化指标和胰岛、肝脏的组织病理学改变。方法大鼠、小鼠各32只,随机分为8组:大鼠对照组、大......
目的探寻提高大鼠胰岛细胞分离纯化技术的方法。方法通过用胶原酶灌注及不连续密度梯度离心法分离纯化胰岛细胞,用DTZ染色计算胰岛......
INTRODUCTIONDiabetes mellitus is the most common disease and its death rate ranks the 8th in the world. Up to now, its i......
目的研究青藤碱(SIN)对同种异体胰岛刺激淋巴细胞的免疫抑制作用以及对胰岛活性和功能的影响。方法以Wistar大鼠胰岛作为刺激原,Le......
本文采用单酶双标法对成人胰岛内分泌细胞进行了双重免疫组化染色。结果发现:(1)成人胰岛为鞘型胰岛,即A,D细胞位于胰岛的周围部形成鞘,......
Islet cell transplantation as a cure for insulin dependent diabetes: current improvements in preserv
【正】 OBJECTIVE: To review the current progress of islet cell transplantation in patients withinsulin-dependent diabete......
Protective effect of glucocorticoid-free immunosuppressive regimen in allogenic islet transplantatio
【正】BACKGROUND: The most common complication after allogenic islet transplantation is rejection. This study was to eva......
柯萨奇B4病毒(CB4V)感染被认为和胰岛素依赖糖尿病(IDDM)原发病有关。我们对体外培养的小鼠胰岛和胰岛细胞经CB4V感染后,检测其胰岛素分泌功能。结果显......
目的探讨小鼠自体胰腺部分切除及自体胰岛的肌肉移植方法,并对术后小鼠进行疗效评价。方法选用C57BL/6小鼠,分为三组,胰腺部分切除后移......
目的介绍一种新的家兔胰岛分离纯化方法并进行纯化后胰岛的外观、活性和胰岛细胞团表面结构等质量分析。方法雄性日本大耳白,采用2......
目的评估移植于Ⅰ型糖尿病犬肝脏中的微囊化新生猪胰岛细胞(NPI)的生物相容性、免疫学特性及生理学特性。方法Ⅰ型糖尿病犬分为A、B......
糖尿病是严重危害人类健康的常见病和多发病,胰岛移植因其手术简单、安全、并发症少,可纠正糖代谢紊乱,尤其是可防止、减缓甚至逆转并......
目的建立胆管内灌注胶原酶分离胰岛与适宜孔径滤网过筛相结合的快速纯化胰岛细胞的方法并评估这种方法的效果。方法清洁级8~12周龄S......
目的探讨正常成人胰岛移植治疗糖尿病的作用。方法 2012年1月至2013年1月健康成人胰腺供体共13例。获取胰腺后经胶原酶消化并进行......
目的构建成年叙利亚金黄地鼠胰岛的分离、纯化及功能鉴定的方法。方法胶原酶V灌注分离成年叙利亚金黄地鼠胰腺,不连续密度梯度法纯......
胰腺部分切除或胰管结扎可以诱导成年大鼠胰腺再生。然而,由于实验模型不同,用胰岛再生能力和方式不尽相同。β细胞再生主要来自β细......
The success achieved over the last decade with islet transplantation has intensified interest in treating diabetes,not o......
Islet transplantation could become an ideal treatment for severe diabetes to prevent hypoglycemia shock and irreversible......
Type 1 diabetes(T1D)is an autoimmune disease wherein the pancreas does not produce enough insulin due to islet beta cell......
At present,proven clinical treatments but no cures are available for diabetes,a global epidemic with a huge economic bur......
目的探索成年大鼠胰岛的分离纯化理想方法,并对获得的胰岛进行体外功能鉴定。方法通过用胶原酶P液灌注分离成年SD大鼠胰岛,不连续密......
Cyclic nucleotide phosphodiesterase 3B is connected to osteopontin and protein kinase CK2 in pancrea
Islets from RIP-PDE3B mice, exhibiting β-cell specific overexpression of the cAMP/cGMP-degrading enzyme phosphodiestera......
In this study, we aimed to examine the electrophysio- logical properties of β-cells in Kir6.2-/- mice using fresh pancr......
Bone marrow increases human islets insulin positive cells in co-culture: quantification with flow cy
We have previously demonstrated that allogeneic human bone marrow (BM) supports human islet function and longevity in vi......
目的:观察实验性糖尿病大鼠腹腔内移植海藻酸钠微囊化成猪胰岛治疗效果。方法:以海藻酸钠-多聚赖氨酸作为制备微囊的材料,将18只糖尿病大......
Aiming at Delaunay triangulation with islets constrains in terrain simulation. A general Delaunay triangulation algorith......
Aim: To identify the influence of pancreatic stellate cell (PSCs) secretions on gene expression profiles of Min6 cells b......
Clostridium histolyticum is used for production of several proteolytic enzymes such as elastase, neutral proteases, clos......