5-Methylcytosine相关论文
Site-specific quantification of 5-carboxylcytosine in DNA by chemical conversion coupled with ligati
5-Methylcytosine (5mC) is the most important epigenetic modification in mammals.The active DNA demethylation could be ac......
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Highly Sensitive Analysis of DNA Methylation by Polymer Monolithic Capillary Liquid Chromatography-M
Background: 5-methylcytosine (5-mC) represents an important epigenetic modification involved in development and is frequ......
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Increased 5-hydroxymethylcytosine and Ten-eleven Translocation Protein Expression in Ultraviolet B-i
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Memory-epigenetics which is the loss of memory due to epigenetic modifications can be due to the silencing of genes invo......
人类基因组中DNA的5-甲基胞嘧啶(5-mC)在人类发育、衰老和疾病中起到至关重要的作用。 TET家族蛋白能够将5-mC 转化成5-羟甲基胞嘧啶......
目的探讨氟暴露剂量和暴露时间对大鼠血、肝、肾和脑中5-甲基胞嘧啶(5-methylcytosine,5-mC)表达的影响,了解氟对不同组织DNA甲基化水......
Objective:Aberrant expression of ten-eleven translocation 1 (TET1) plays a critical role in tumor development and progre......
Increased 5-hydroxymethylcytosine and Ten-eleven Translocation Protein Expression in Ultraviolet B-i
Background:DNA hydroxymethylation refers to a chemical modification process in which 5-methylcytosine (5mC) is catalyzed......
目的探讨结肠癌组织中5-甲基胞嘧啶(5-methylcytosine,5-mC)表达与患者临床病理特征的相关性。方法采用结肠癌组织芯片(HColA160Su......
用B3LYP/6-311+G(d))及MP2/6-311+G(d)计算方法,对5-甲基胞嘧啶与BH3所形成复合物及异构化反应进行了研究,获得了6种复合物及4个异构化过渡态.......
采用密度泛函理论方法研究了在气相中5-甲基胞嘧啶分子的异构体,通过频率表征,得到14种稳定的异构体,计算了各异构体的总能量、零点能......
采用密度泛函理论,在B3LYP/6-31++G//B3LYP/6-31G基组水平上对5-甲基胞嘧啶互变异构体及质子转移机理进行了研究,获得了10种5-甲基胞......
A high methionine,low folate and vitamin B6/B12 containing diet can be associated with memory loss b
Memory-epigenetics which is the loss of memory due to epigenetic modifications can be due to the silencing of genes invo......
迄今为止,不少人认为5-甲基胞嘧啶的存在可能是基因突变的“热点”。然而,事实上5-甲基胞嘧啶作为一种稀有碱基,本来就是许多真核......
5-甲基胞嘧啶是一个非常重要的医药中间体,用来制备抗病毒和抗肿瘤等药物。以5-甲基脲嘧啶为原料,先与三氮唑反应制得中间体5-甲基......
HPLC analysis is important for determination of total level on DNA methylation in plants. It can be used to help charact......