基于VHSE(Principal component score vector of hydrophobic,steric,and electronic properties)结构表征方法,采用支持向量机结......

氰乙酸乙酯经亚硝化、与盐酸胍在乙醇钠存在下缩合闭环、Pd／C催化还原得2，4，5-三氨基-6-羟基嘧啶，与甲酸环合得鸟嘌呤，再经乙酰化、氯化......