Anticonvulsant相关论文
,Design, molecular docking, synthesis, characterization, biological activity evaluation (against MES
BACKGROUND:Among the reported potential agents to treat the epilepsy,sulphonamides are important and their significance ......
Progress in studies on the role of gamma-aminobutyric acid type A receptor in convulsion: a short re
Convulsion is the medical condition where body muscles contract and relax rapidly and repeatedly,resulting in an uncontr......
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
Synthesis and anticonvulsant activity of 1-substituted benzyl-N-substituted-1, 2, 3-triazole-4-for-m
Substituted benzyl azids were synthesized through the reaction of substituted benzyl chloride and sodium azid, which sub......
Progress in studies on the role of gamma-aminobutyric acid type A receptor in convulsion: a short re
Convulsion is the medical condition where body muscles contract and relax rapidly and repeatedly,resulting in an uncontr......
Synthesis and anticonvulsant activity of 7-benzylamino-4, 5-dihydro- [ 1, 2, 4] triazolo[ 4, 3-a] qu
A series of 7-substituted-benzylamino-4, 5-dihydro-[ 1,2, 4]triazolo[4, 3-a] quinoline derivatives was synthesized and e......
以对氨基酚为起始原料合成了一系列2-(4-(1,2,4-三唑)-苯氧基乙酰腙衍生物(5a-5o)。通过核磁共振氢谱和碳谱确证了目标化合物的结......
目的合成一系列3-芳基-1H-5-取代吡唑酰腙类化合物,用于抗癫痫和抗炎活性筛选.方法以苯乙酮(或取代苯乙酮)为起始原料与草酸二乙酯......
合成了11种γ-氨基丁酸异硫氰酯偶联去甲斑蝥素与取代苯胺目标化合物，其结构经IR、^1H NMR和HR—MS测试技术确证。抗惊厥活性初步测......
癫痫是一种由多种原因引起的脑部神经元群阵发性异常放电所致的植物神经功能异常的疾病，以反复发作性、短暂性、通常为刻板性的中枢......
3，5-二氯-2-戊酮经硫氰化、闭环反应得到4-甲基-5-（2-氯乙基）-2-羟基噻唑，和磷酰氯反应后用钯炭催化氢解脱氯，制得盐酸氯美噻唑，总收率61......
Synthesis and evaluation of 4-substituted semicarbazones of levulinic acid for anticonvulsant activi
Objective: A series of 4-aryl substituted semicarbazones of levulinic acid (4-oxo pentanoic acid) was designed and synth......
目的:探讨抗惊厥药所致药物超敏综合征(DHS)的临床特征.方法:回顾分析19例抗惊厥药所致DHS患者的临床表现、实验室检查、治疗方法......
以戊四氮诱发小鼠惊厥为模型，观察单用牛磺酸及联合用苯巴比妥钠的抗惊厥作用，并测定牛磺酸对脑中ｒ－氨基丁酸（ＧＡＢＡ）、牛磺酸、谷氨酸水平的影......
目的 探讨抗癫痫药物（AED）卡马西平（CBZ）和丙戊酸钠（VPA）血清中浓度与唾液中浓度的相关性及其CBZ、VPA在唾液中的稳定性，明确唾液监测AED......
根据药物设计原理,设计合成了一系列二甲吡唑联苯并噻唑衍生物并且研究其抗惊厥活性。实验结果表明:在所有衍生物中,当取代基为烷......
奥卡西平（oxcarbazepine，1），化学名为10，11-二氢-10-氧代-5H-二苯[b，f]氮杂[艹卓]-5-甲酰胺，由瑞士Novartis公司研发，1990年首次在丹麦上市......
