CERAMIDE相关论文
Gelatin polypeptides from Pacific cod skin alleviate skin tissue damage induced by ultraviolet radia
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Codelivery of Docetaxel and Ceramide Enhanced Synergistic Cancer Therapy by Lipid-based Nanosuspensi
Combination therapy as novel therapeutic strategies has attracted great attention in the field of anti-cancer therapy.Th......
Weightlessness or simulated weightlessness would induce structural adaptation of arteries,but the effect of it on the ca......
Introduction: Chronic exposure to noise might induce liver damage including increased oxidative stress in hepatocyte,liv......
Improvement of noise-caused cognitive dysfunction of mice through inhibiting acid sphingomyelinase/c
Introduction: Noise pollution is one of the critical public health problems which can not only impair the auditory syste......
we aimed to investigate the change of acid sphingomyelinase(ASM)/ceramide(Cer)after simulated weightlessness and the rol......
Neritinaceramides A-E, New Ceramides from the Marine Bryozoan Bugula neritina Inhabiting South China
Five new ceramides, neritinaceramides A (1), B (2), C (3), D (4) and E (5), together with six known ceramides (6-11), tw......
Qualitative and quantitative analysis of ceramide species in biological samples in an untargeted lip
Ceramide plays important roles in several aspects such as cell apoptosis, growth and differentiation, as well as signal ......
Inhibition of extracellular vesicle pathway using neutral sphingomyelinase inhibitors as a neuroprot
Traumatic brain injury is a sudden trauma or blow on the head,and severe traumatic brain injury is a major cause of deat......
目的通过皮肤机械屏障障碍模型鼠来研究参苓白术散(Shen Ling Bai Shu Power,SLBZP)对皮肤屏障功能的影响。方法取健康小鼠50只,随......
目的 探讨酸性鞘磷脂酶(acid sphingomyelinase,ASM)/神经酰胺(ceramide,Cer)通路在血管紧张素Ⅱ(angiotensin Ⅱ,Ang Ⅱ)致动脉内......
A new ceramide, (2S,3R,4E)-l,3-dihydroxy-2-[(hexadecanoyl)amino]-nonadeca-4-ene (1), chol est-5-en-3β,7β,19-triol (2),......
,Ceramide induces apoptosis in human lung adenocarcinoma A549 cells through mitogen-activated protei
Aim: To provide experimental data for further research on the signal transduction of apoptosis in lung adenocarcinoma ce......
Hispidulin,a polyphenolic flavonoid extracted from the traditional Chinese medicinal plant S involucrata,exhibits anti-t......
Leptin resistance in endothelial cells leads to vascular endothelial dysfunction,which is the beginning and crucial link......
A Lipidomic Study of the Effects of N-methyl-N’-nitro-N-nitrosoguanidine on Sphingomyelin Metabolism
Systems biology is a new and rapidly developing research area in which, by quantitatively describing the interaction amo......
Influence of short chain ceramides and lipophilic penetration enhancers on the nano-structure of str
该文从挂篮荷载计算、施工流程、支座及临时固结施工、挂篮安装及试验、合拢段施工、模板制作安装、钢筋安装、混凝土的浇筑及养生......
目的探讨模拟失重大鼠颈总动脉对神经酰胺(ceramide, Cer)调控的敏感性改变及其机制。方法雄性Sprague-Dawley大鼠48只,按体重配对......
Separation and Detection of Ceramides by HPLC Followed by Evaporative Light-Scattering Detection and
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
Cytotoxicity and Apoptotic Effect of Phytoceramide IV Containing Liposomes on Murine Mastocytoma Cel
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
目的建立稳定转染bcl-2的鳞状细胞癌(鳞癌)细胞系,研究人皮肤鳞癌细胞凋亡的相关通路。方法应用脂质体介导的基因转染法.将含有bcl......
TMSG-1 is a newly discovered tumor metastasis suppressor gene, which plays important roles in promoting apoptosis and in......
Objective To investigate the potential mechanisms of cell death after the treatment with ceramide. Methods MTT assay,DNA......
鞘脂是细胞膜脂质双层的主要结构成分并调控细胞重要生理功能,其代谢异常与多种慢性疾病密切相关。细胞鞘脂代谢以神经酰胺为中心,包......
AIM: To test the hypothesis that hydrolysis of sphingomyelin to ceramide changes the composition of tight junctions (TJs......
目的探讨长期酒精暴露与胰岛素敏感性之间的关系并探讨其相关的分子机制;观察神经酰胺在酒精引起胰岛素抵抗过程中的可能作用。方......
以甜菜、甜菜渣和甜菜糖蜜为原料,提取测定其功能性成分神经酰胺的含量,为提取利用神经酰胺提供理论依据。结果表明,甜菜、甜菜渣及甜......
AIM:To investigate the effect of ceramide on the cell cycle in human hepatocarcinoma Bel7402 cells.Possible molecular me......
MicroRNAs (miRNAs) are 21-23 nucleotide (nt), endogenous RNAs that regulate gene expression by targeting mRNAs for direc......
A new C-18 phytosphingosine derivative (1) was isolated from the fruiting bodies of Tuber indicum.Its structure was esta......
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
神经酰胺是一种鞘磷脂分子,作为细胞内第二信使,调控细胞增殖、分化、衰老和凋亡等生命活动。肺动脉高压是一类以肺小动脉重构和肺......
研究雷公藤(Tripterygium wilfordii Hook. f.)根心部分的化学成分,采用硅胶柱色谱法进行分离,从其氯仿提取物中分到两个神经酰胺......
从海南省三亚附近海域采集的针荔海绵Raphiedotethya sp.中分离到1个新神经酰胺和1个甾醇苷。经波谱分析和化学分析确定了它们的化......
神经鞘苷参与细胞识别、细胞粘合,调节细胞免疫、决定血型等作用,具有免疫调节、抗肿瘤、抗病毒、抗肝毒等多种药理活性.神经酰胺......
酸性鞘磷脂酶(acid sphingomyelinase,ASM)是一种通过水解鞘磷脂产生酰胺的重要溶酶体酶。最近的调查结果显示,在酰胺诱导细胞凋亡的......
目的观察神经酰胺阻断剂对高浓度葡萄糖培养的人脐静脉内皮细胞(HUVECs)胰岛素信号通路PKB/eNOS mRNA表达的影响。方法高浓度葡萄糖......
海藻糖和神经酰胺在皮肤保湿中具有重要作用。利用原位X射线散射设备,研究了在干燥和升降温过程中海藻糖与神经酰胺之间的分子相互......
从莳萝曲网海绵(Sigmadocia cymiformis Esper)的乙醇提取物中分离得到的4个结晶性化合物. 通过波谱分析及化学降解等方法鉴定出它......
目的介绍了神经酰胺的抗肿瘤特性及其作为肿瘤抑制剂的原理及应用前景.方法通过查阅大量国内外有关神经酰胺的抗肿瘤特性方面的文......
海洋药物具有显著的药理稳定性和强效性,毒副作用相对较小,对防治癌症、艾滋病、心脑血管病、老年病等疑难杂症具有独特的作用,已......
神经酰胺和鞘胺醇-1-磷酸是具有生物活性的鞘磷脂,它们不仅是构成细胞膜的重要组分,也可以作为第二信使在细胞信号转导中发挥重要......
从细基江蓠中分离及鉴定出十五碳酸甘油酯(1),全饱和的神经酰胺(2),N-苯基-2-(艹佘)胺(3),24-亚甲基胆甾醇(4),硬脂酸和硬脂酸甲酯......
目的 探讨外源性神经酰胺诱导人结肠癌HT-29细胞的凋亡作用。方法 采用光镜、电镜、荧光显微镜和琼脂糖凝胶电泳方法检测C2-神经酰......
目的评价老化的血小板中的神经酰胺对输血相关急性肺损伤(transfusion-related acute lung injury,TRALI)的作用机制。方法通过脂......