建立一种简便、灵敏、准确的液相色谱-串联质谱法以同时测定人血浆中氟吡汀及其活性代谢物D-13223浓度.本文采用三重四级杆液质联......

Aim: Learning and memory are greatly modified by stress and hippocampal synaptic plasticity such as long-term potentiati......

Flupirtine 为新型结构镇痛药,化学名称为N-[2-氨基-6-(4-氟-苯甲氨基)吡啶-3]氨基甲酸乙酯,其结构为:目前,已对它的药理活性进行......

目的 根据5个民族受试者口服氟吡汀后的血药浓度数据建立氟吡汀的群体药动学模型,从而实现个体化用药.方法 选择汉、蒙、朝、维和......

Objective:Flupirtine is a non-opioid analgesic without antipyretic or antiphlogistic properties but with favorable toler......

目的研究中国朝鲜族和汉族健康受试者单剂量口服马来酸氟吡汀的药动学。方法选择健康受试者20例（朝鲜族和汉族各10例），单剂量口服马来......

氟吡汀是一种新型非阿片类止痛药，为选择性神经元钾通道开放剂，具有止痛、松弛肌肉和保护神经的作用。其最主要的适应证为肌紧张相关......

Flupirtine is the first representative in a class of triaminopyridines that exhibits pharmacological properties leading ......

Fibromyalgia is characterized by the primary symptoms of persistent diffuse pain,fatigue,sleep disturbance and cognitive......

目的制备马来酸氟吡汀口腔崩解片,并对其质量进行评价。方法正交实验优化处方,以片剂崩解时限和溶出度作为评价指标制备马来酸氟吡......