HNF4a相关论文
目的:肝细胞移植是遗传性和终末期肝脏疾病的有效治疗方法。但是,原代人类肝细胞来源匮乏、体外难于长期培养和保持功能等问题限制......
目的：探讨肝癌细胞经HNF4a慢病毒转染后的细胞生物学变化. 方法：经过gateway技术构建HNF4a-IRES-hrGFP以及CMV-luciferase2-maket2慢......
Effect of genetic variants in KCNJ11, ABCC8, PPARG and HNF4A loci on the susceptibility of type 2 di
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Analysis of the HNF4A isoform-regulated transcriptome identifies CCL15 as a downstream target in gas
Objective:Hepatocyte nuclear factor 4α (HNF4A) has been demonstrated to be an oncogene in gastric cancer (GC). However,......
背景与目的 肿瘤缺氧与转移和放化疗耐药相关.氧敏感相关基因具有临床价值,对预后有重要意义.在本研究中,我们研究了2-氧化戊二酸......
Effect of genetic variants in KCNJ11, ABCC8, PPARG and HNF4A loci on the susceptibility of type 2 di
Background KCNJ11, ABCC8, PPARG, and HNF4A have been found to be associated with type 2 diabetes in populations with dif......
目的 构建肝细胞核因子4α（hepatocyte nuclear factor 4 alpha,HNF4A）的过表达慢病毒载体,并对其进行病毒包装、鉴定与滴度测定,为......
背景与目的肿瘤缺氧与转移和放化疗耐药相关。氧敏感相关基因具有临床价值,对预后有重要意义。在本研究中,我们研究了2-氧化戊二酸......
目的探究HNF4A在结直肠肿瘤进展中的作用。方法构建HNF4A过表达或敲除的结直肠癌细胞系,通过实时定量PCR和Western blot检测构建的......
目的明确HNF4A在结直肠癌发生发展中的作用及机制,探究HNF4A作为结直肠癌治疗新靶点的理论依据。方法收集117例结直肠癌患者的临床......
