MITOCHONDRION相关论文
目的:研究解毒化瘀颗粒对氧化损伤人肝细胞L02的影响,并探讨其作用机制。方法:采用0.1 mmol/L Hn 2On 2干预1 h构建人肝......
Antioxidant activities of cold-nature Tibetan herbs are signifcantly greater than hot-nature ones an
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Phosphorescent Bis(N-heterocyclic carbene)Iridium(Ⅲ)Complexes as Mitochondria-Targeted Theranostic a
With a diverse range of mitochondrial targeted drugs currently in clinical trials,targeting mitochondria as a cancer the......
Introduction Mitochondrion is power house of the cell; its an important organelle involving in energy homeostasis.Change......
In this study, we report the basic characteristics of the cattle tick mitochondrial genome, in cluding structural organi......
Mitochondrial genome of Babesia orientalis,apicomplexan parasite of water buffalo (Bubalus babalis,L
Apicomplexan parasites of the genus Babesia,Theileria and Plasmodium are very closely related organisms.Interestingly,th......
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Complete mitochondrial genome of Pseudoperonospora cubensis in the alpine steppe of the Tibetan Plat
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Steroid alkaloids have long been suggested as potential anti-cancer compounds.However, the underlying mechanisms that ho......
Drug resistance is one of the critical reasons leading to tailure in chemotherapy.Enormous studies have been focused on ......
Effects of gestational hypercholesterolemia on mitochondrial biogenesis and function in full term hu
Gestational hypercholesterolemia increases susceptibility to mitochondrial dysfunction.This study was aimed to determine......
Oridonin(1)is a complex ent-kaurane diterpenoid isolated from Isodon rubescens which displays remarkable antitumor activ......
Many Phosphorescent iridium complexes potent candidates for photodynamic therapeutic agents....
Platinum-based anticancer drugs usually bind to purine bases through covalent bonds to inhibit DNA replication and cause......
The heart requires continuous ATP availability that is generated in the mitochondria. Although studies using the cell cu......
Pollen developmental defects in ZD-CMS rice line explored by cytological,molecular and proteomic app
Cytoplasmic male sterility(CMS)is a widely observed phenomenon,which is especially useful in hybrid seed production.......
Phylogenomic Analysis of Transcriptomic Sequences of Mitochondria and Chloroplasts for Marine Red Al
The chloroplast and mitochondrion of red algae(Phylum Rhodophyta)may have originated from different endosymbiosis.In......
Phylogenomic Analysis of Transcriptomic Sequences of Mitochondria and Chloroplasts of Essential Brow
The chloroplast and mitochondrion of brown algae(Class Phaeophyceae of Phylum Ochrophyta)may have originated from di......
谷胱革肽是细胞内重要的抗氧化损伤物质之一,以NADH诱导的牛心肌线粒体脂质过氧化体系为模型,研究了谷胱甘肽的抗氧化作用。结果表明,一定......
A ratiometricfluorescent hybrid nanoprobe CDs-1 for arginine (Arg), exhibiting high sensitivity (the limit of detection,......
目的探讨葡萄籽原花青素对睡眠呼吸暂停模式低氧大鼠海马区线粒体损伤及学习记忆的影响。方法80只雄性SD大鼠分成对照组、模型组、......
目的研究低温对大鼠学习记忆能力及海马区细胞线粒体融合基因与分裂基因mRNA表达的影响。方法选取健康Wister大鼠32只,按低温处理时......
Altered mitochondria and Bcl-2 expression in the hippocampal CA3 region in a rat model of acute epil
BACKGROUND: Previous studies have shown that the mitochondrial structure and function are damaged in animal models of ep......
Mitochondrial and nuclear changes in hippocampal neurons in a lithium-pilocarpine-induced status epi
BACKGROUND: Mitochondrial damage plays a key role in neuronal damage.OBJECTIVE: To observe ultrastructural damage to mit......
Hippocampal mitochondrial cytochrome C oxidase activity and gene expression in a rat model of chroni
The present study established a rat model of chronic cerebral ischemia using bilateral common carotid artery permanent l......
Genistein suppresses the mitochondrial apoptotic pathway in hippocampal neurons in rats with Alzheim
Genistein is effective against amyloid-βtoxicity, but the underlying mechanisms are unclear. We hypothesized that genis......
Leber遗传性视神经病变(LHON)是一种常见的与线粒体突变相关的母系遗传性疾病,在不同种族人群的LHON家系中,有50%以上是由于线粒体D......
目的探讨氟中毒对人肝癌细胞(HepG2)线粒体凋亡及其相关蛋白的影响。方法体外培养HepG2细胞24 h,分别采用0(对照)、1、3、6、9 mmol/L氟......
脓毒性心肌病的发生率和病死率均较高,是脓毒症患者常见的死亡原因之一。脓毒性心肌病的发病机制尚不十分清楚,心肌细胞线粒体功能障......
目的探讨Klotho蛋白(一种单向跨膜蛋白)对脓毒症急性肾损伤(AKI)小鼠的保护作用及其作用机制。方法选取6~8周龄、SPF级健康雄性C57BL/6......
Mitochondrial and nuclear changes in hippocampal neurons in a lithium-pilocarpine-induced status epi
BACKGROUND: Mitochondrial damage plays a key role in neuronal damage.OBJECTIVE: To observe ultrastructural damage to mit......
Hippocampal ultrastructural changes and apoptotic cell death in rats following endurance training an
BACKGROUND: Exhaustive exercise can lead to apoptosis of skeletal muscle cells and myocardial cells as a result of patho......
目的:通过建立大鼠离心运动后肱三头肌超微结构损伤的模型,从肱三头肌线粒体超微结构变化和线粒体钙代谢方面分析和探讨线粒体在运......
铂类配合物5a是从200多个新合成的铂类配合物中筛选得到.该文旨在研究其对多种肿瘤细胞的体外抗肿瘤作用,对正常细胞的毒性,同时对......
Phylogenomic analysis of transcriptomic sequences of mitochondria and chloroplasts of essential brow
本文通过对荣华二采区10...
Phylogenomic analysis of transcriptomic sequences of mitochondria and chloroplasts for marine red al
本文通过对荣华二采区10...
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,Effects of Shark Hepatic Stimulator Substance on the Function and Antioxidant Capacity of Liver Mit
This study was carried out to investigate whether shark hepatic stimulator substance (HSS) can prevent acute liver injur......
目的研究β-淀粉样蛋白(β-amyloid )对原代培养的大鼠脑海马神经细胞内钙稳态和线粒体通透性转运孔(mitochortrial permebility t......
FOXO1 inhibition potentiates endothelial angiogenic functions in diabetes via suppression of ROCK1/D
该文从挂篮荷载计算、施工流程、支座及临时固结施工、挂篮安装及试验、合拢段施工、模板制作安装、钢筋安装、混凝土的浇筑及养生......
目的探讨儿童线粒体脑肌病高乳酸血症和卒中样发作综合征(MELAS)临床的误诊原因,提高对该病的早期诊断和治疗能力。方法对1例长期......
目的探讨慢性间歇低氧(CIH)对大鼠颏舌肌细胞线粒体功能的影响及脂联素干预作用。方法健康雄性Wistar大鼠39只,采用随机数字表法分......
[目的]研究二硫化碳(carbon disulfide,CS2)染毒对大鼠睾丸支持-生精共培养细胞凋亡线粒体途径相关基因表达的影响。[方法]选用22~......
[目的]研究三(2-氯乙基)磷酸酯[tris(2-chloroethyl)phosphate,TCEP]对肝细胞线粒体功能的影响。[方法]用0.00(溶剂对照组)、3.12......
The Association between the C5263T Mutation in the Mitochondrial ND2 Gene and Coronary Heart Disease
Objective This study aimed to investigate the genetic background of mitochondrial genes in young patients with Coronary ......
目的 探讨脓毒症时大鼠肾脏线粒体的损伤情况.方法 采用腹腔注射内毒素(LPS)建立脓毒症大鼠模型.30只SD大鼠随机分为对照组、6 h脓......
Hippocampal mitochondrial cytochrome C oxidase activity and gene expression in a rat model of chroni
The present study established a rat model of chronic cerebral ischemia using bilateral common carotid artery permanent l......
目的 探讨电离辐射诱导的人线粒体基因COXI、ND1和ND6表达的变化.方法 用60Co γ射线(1、3、5、8和10 Gy)照射指数增长期的人淋巴......