hippoca相关论文
Genistein suppresses the mitochondrial apoptotic pathway in hippocampal neurons in rats with Alzheim
Genistein is effective against amyloid-βtoxicity, but the underlying mechanisms are unclear. We hypothesized that genis......
Differentiating between Alzheimer’s disease, amnestic mild cognitive impairment, and normal aging vi
Diffusion kurtosis imaging can be used to assess pathophysiological changes in tissue structure and to diagnose central ......
Brain ischemia induces serine phosphorylation of neuronal nitric oxide synthase by Ca~(2+)/calmoduli
AIM: To investigate whether brain ischemia induces serine phosphorylation of neuronal nitric oxide synthase(nNOS) by Ca2......
D-galactose has been widely used in aging research because of its efficacy in inducing senescence and accelerating aging......
Serine 707 of APPL1 is Critical for the Synaptic NMDA Receptor-Mediated Akt Phosphorylation Signalin
Accumulating evidence indicates that the synaptic activation of N-methyl-D-aspartate receptors(NMDARs) has a neuroprotec......
The total flavonoids extracted from Xiaobuxin Tang reverse the hyperactivity of hypothalamic-pituita
Objective To investigate the effect of XBXT-2 on the activity of hypothalamic-pituitary-adrenal(HPA)axis in chronic mild......
In vitro cultured human neuroblastoma SH-SY5Y cells were pretreated with 50 or 5 μg/mL geniposide for 12 hours and expo......
Objective To investigate the effect of oleuropein(OE) on long term potentiation(LTP) at hippocampal perforant path-denta......
EVALUATION OF NEUROPROTECTIVE EFFECTS OF LONG-TERM LOW DOSE HORMONE REPLACEMENT THERAPY ON POSTMENOP
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
目的 探讨慢性应激抑郁状态对大鼠海马神经干细胞的影响.方法 应用慢性不可预知温和应激和孤养法建立抑郁模型,分为对照组、CUMS 1......
目的探讨切割穹隆海马伞大鼠海马胆碱能神经再生过程中Lhx8的作用。方法 72只SD大鼠随机分成4组,每组18只。所分的4组分别为:对照......
精神分裂症是一种严重精神病,以幻觉、思维及行为紊乱和社会功能退化为特征,患病率为1%,给个人、家庭及社会带来极大负担.精神分裂......
本研究比较了不同生长因子对人胚胎脑海马区神经干细胞(NSCs)体外生长的影响.取胎龄8~12周的人胚胎脑海马,按基础培养液中生长因子......
目的 探讨慢性束缚应激(CRS)对小鼠认知功能的影响,观察海马不同亚区(CA1、CA3和DG区)星形胶质细胞(AS)的激活情况,明确慢性应激对海马的......
目的探讨缬草对慢性应激导致的抑郁大鼠体重、行为、血清皮质醇和海马Caspase-3阳性细胞数量的影响。方法50只大鼠被分为正常对照......
目的:探讨海洛因成瘾者停止用药后静息状态下脑功能的变化情况。方法:对海洛因成瘾者在停止使用海洛因3天(10人),1个月(10人)以及2个月(14......
目的:观察黄芪注射液对脑缺血再灌注大鼠海马神经元形态学和Apaf-1表达的影响。方法 SD大鼠随机分为假手术组、脑缺血再灌注组(再灌......
目的和方法:采用膜片钳全细胞记录技术观察新生大鼠海马神经元体外分散培养过程中,基本离子通道和膜参数随培养天数延长而变化的规......
目的:探讨去势雌性大鼠海马区Tau蛋白Alzheimer样磷酸化的变化. 方法: 建立大鼠双侧卵巢切除(OVX)模型, 分别于术后1周、2周、3周......
目的:探索低压缺氧延迟预适应小鼠海马差异表达基因。方法:将近交系Babl/e小鼠放入减压舱,模拟海拔7000m高度减压2.5h/d,连续3d。第3次减......
目的探讨Noggin基因对成年大鼠海马内Nestin及GFAP表达的影响.方法反义寡核苷酸技术封闭内源性Noggin基因的表达,免疫组化法检测成......
急性应激和长期慢性应激均可损伤脑内的海马和前额叶,继而降低动物或人的学习记忆能力。采用4周反复力竭游泳运动方式建立力竭运动......
目的探讨黄芪多糖(APS)对阿尔茨海默病(AD)模型小鼠的影响。方法小鼠随机分成对照组、模型组、吡拉西坦组、APS高、中、低剂量组(8......
目的:探讨瑞芬太尼和丙泊酚对老年大鼠学习记忆及其海马胆碱乙酰转移酶(ChAT)表达的影响。方法:雄性18月龄SD大鼠50只,随机分成5组(n=10......
目的探讨Janus激酶/信号传导和转录激活蛋白3(JAK/STAT3)通路阻断对新生大鼠缺氧缺血性脑病(HIE)的影响,为HIE的基因治疗提供依据......
目的探讨神经导航下锁孔入路选择性海马杏仁核切除术治疗顽固性内侧颞叶癫痫的可行性。方法总结分析18例神经导航下锁孔入路选择性......
目的探讨腹部的手术操作对老年大鼠学习认知能力的影响和海马CA1区胆碱乙酰转移酶(CHAT)阳性神经元的变化以及石杉碱甲干预的结果。......
目的研究电针是否通过调节老年性痴呆模型小鼠海马N-甲基-D-天冬氨酸型谷氨酸受体(NMDARs)的表达,保护认知能力,探讨电针防治老年......
目的观察鹅膏蕈氨酸对大鼠海马神经元的毒性作用,探讨鹅膏蕈氨酸的毒理学机制。方法成年Wistar雄性大鼠,侧脑室1次性注射鹅膏蕈氨酸(I......
The present study assessed the influence of medium-intensity (treadmill at a speed of 19.3 m/min until exhaustion) and h......
Differentiating between Alzheimer’s disease, amnestic mild cognitive impairment, and normal aging vi
Diffusion kurtosis imaging can be used to assess pathophysiological changes in tissue structure and to diagnose central ......
目的:观察中药复方抗痫灵对戊四氮致痫大鼠海马组织中C—fos蛋白表达水平的影响,探讨中药复方抗痫灵治疗癫痫的可能作用机制。方法:将......
目的研究钾通道开放剂尼可地尔对链脲佐菌素(STZ)诱导的糖尿病小鼠认知功能障碍的保护作用。方法对C57BL/6J小鼠采用STZ诱导1型糖尿......
背景:脾虚证不仅对人体的免疫系统和消化系统等产生不同程度的影响,且脾与脑存在密切的生理联系,因此脾虚证还会影响到中枢神经系统......