Methyltransferase相关论文
SETD8/SET8/Pr-SET7/KMT5A is the sole protein lysine methyltransferase(PKMT)that catalyzes the monomethylation of histone......
The NSD family of protein lysine methyltransferases consists of NSD1,NSD2(WHSC1/MMSET)and NSD3(WHSC1L1).The NSD methyltr......
Methyltransferase Dnmt3a Upregulates HDAC9 to Deacetylate TBK1 for Activation of Antiviral Innate Im
Epigenetic regulation of innate immunity needs further identification.Dnmt3a,a de novo DNA methyltransferase,is highly e......
Recent outbreak of flavivirus Zika virus(ZIKV)in America has urged the basic as well as translational studies of thi......
Methylation of Histone 3 Lysine 4(H3K4)is a critical chemical modification for epigenetic regulation and plays impor......
Aim:To characterize sphingosine methyltransferase in rat tissues.Methods:By using S-adenosyl-L-(methyl-3H) methionine,en......
Many flaviviruses are significant human pathogens. The plus-strand RNA genome of a flavivirus contains a 5’terminal cap......
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Plant cell walls are complex structures that offer structural and mechanical support to plant cells and are ultimately r......
,MeNA, Controlled by Reversible Methylation of Nicotinate, Is an NAD Precursor that Undergoes Long-D
Nicotinamide adenine dinucleotide (NAD) biosynthesis,including synthesis from aspartate via the de novo pathway and from......
目的 验证6-氧-甲基鸟嘌呤-DNA甲基转移酶(MGMT)基因启动子CpG岛高甲基化在结直肠癌发生、发展中的作用,并探讨联合检测基因甲基化......
Arsenic-contaminated water is a serious hazard for human health.Plankton plays a critical role in the fate and toxicity ......
Arsenic(As)is a well-recognized toxicant and carcinogen.Chronic exposure to inorganic arsenic causes a range of human ca......
目的研究组蛋白甲基转移酶PR结构域锌指蛋白9（PR domain zinc finger protein 9，PRDM9）对牙周膜干细胞（periodontal ligament stem cel......
暴露在核小体表面的N-末端尾部可发生共价修饰,这些共价修饰可以影响组蛋白和DNA结合的紧密程度,从而影响DNA的表达,被称之为"组蛋......
DNA甲基化是真核生物表观遗传学中一种重要的基因表达调控方式，是一种酶催化的修饰过程。其是在DNA甲基转移酶催化下，将甲基基团转移......
Predictive value of MGMT promoter methylation on the survival of TMZ treated IDH-mutant glioblastoma
Objective:O6 methylguanine-DNA methyltransferase(MGMT)promoter methylation is a biomarker widely used to predict the sen......
AIM: To explore the alteration of DNA methyltransferase expression in gastric cancer and to assess its prognostic value.......
Preparation, crystallization and preliminary X-ray diffraction analysis of PH1948, predicted RNA met
RNA methyltransferase is responsible for transferring methyl and resulting in methylation on the bases or ribose ring of......
[Objective] The aim of experiment was to lay molecular foundation for studying maturity mechanism of banana after harves......
Effect of antisense DNMT3b gene eukaryotic expression plasmid on expression of the DNMT3b gene in hu
【正】BACKGROUND: Hypermethylation of the promoter region is one of the major mechanisms of tumor suppressor gene inacti......
柚皮素具有多种生物活性，但是水溶性较差，植物中存在多种酶能够对柚皮素进行结构修饰，生成的柚皮素衍生物能够增加水溶性、提高生物利......
Influence of DNA methyltransferase 3b on FHIT expression and DNA methylation of the FHIT promoter re
BACKGROUND:Alterations in DNA methylation occur during the pathogenesis of human tumors.In this study, we investigated t......
Henl蛋白是一类作用于RNA3’末端的甲基转移酶，研究表明其同源物在植物、动物和细菌中均存在。不同来源的Henl蛋白在结构和功能上存......
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Inflammatory bowel disease(IBD)is a consequence of the complex,dysregulated interplay between genetic predisposition,env......
3-76 Histone Methyltransferase NSD2 is Transcriptionally Down-regulated by p53 Upon Etoposide-induce
Nuclear Receptor-binding SET Domain 2 (NSD2) is a SET domain-containing protein lysine methyltransferase (PKMT) implicat......
综述了复制蛋白的几个关键的结构域(解螺旋酶的功能区,依赖RNA的RNA聚合酶(RdRp)的核心区域,类似糜蛋白酶的蛋白酶区域,转甲基酶结......
O^6-methylguanine-DNA methltransferase(MGMT) gene expression in 6 Mer^+(HeLa S3,SMMC-7721,SGC-7901,B-239,AGZY83-a,and Cc......
为了研究有效的水疱性口炎病毒疫苗,控制水疱性口炎疾病的蔓延,用甲基化能力致弱的重组水疱性口炎病毒VSV-E1764A,VSV-S1827A,VSV-......
BACKGROUND Novel therapeutic strategies are urgently needed for patients with a delayed diagnosis of pancreatic ductal a......
近年来表观遗传学修饰在恶性肿瘤发生发展中的作用日益引起人们重视。白血病患者中存在着组蛋白修饰的异常,H3K9甲基化失平衡与白......
The tumor selectivity of alkylating agents that produce guanine O6-chloroethyl (laromustine and carmustine) and O6-methy......
Protein arginine methyltransferases(PRMTs) catalyze the methylation of a variety of protein substrates, many of which ha......
DNA methyltransferase (DNMTs) expression in cervical cancer tissues and its relationship with HPV in
Objective:To study the DNA methyltransferase (DNMTs) expression in cervical cancer tissues and its relationship with hum......
O~6-METHYLGUANINE-DNA METHYLTRANSFERASE ACTIVITY AND SENSITIVITY OF 20 CHINESE TUMOR CELL STRAINS TO
O6-methylguanine-DNA methyltransferase (MGMT) plays an important role in repairing alkylated DNA. MGMT activity as well ......
DEPLETION OF O~6-METHYLGUANINE-DNA METHYLTRANSFERASE ACTIVITY AND POTENTIATION OF 1-(4-AMINO-2-METHY
O6-methylguanine-DNA Methyltransferase (MGMT) can specifically repair the DNA demage Induced by chioroethylnitrosoureas ......
Combining protein arginine methyltransferase inhibitor and antiprogrammed death-ligand-1 inhibits pa
BACKGROUND Immunotherapy targeting programmed death-1(PD-1)or programmed deathligand-1(PD-L1)has been shown to be effect......
O6-methylguanine DNA methyltransferase(MGMT)gene promoter methylation plays an important role in colorectal carcinogenes......
ue＊M＃’＃dkB4＃＃8＃”专利申请号:00109“7公开号:1278062申请日:00.06.23公开日:00.12.27申请人地址:（100084川C京市海淀区清华园申请人:清......
