Mitogen相关论文
BACKGROUND:Activated N-methyl-D-aspartate(NMDA) receptor is involved in the formation of chronic neuropathic pain,and it......
Evidence for a role of mitogen-activated protein kinases in the treatment of experimental acute panc
Acute pancreatitis(AP) is an inflammatory disease characterized by acute inflammation and necrosis of the pancreatic par......
植物血凝素(PhytochaemagglulininPHA)为一强有力的非特异性有丝分裂原(mitogen),在体外与淋巴细胞共同培育时,可引起淋巴细胞有......
为了观察轻微病变型肾病(MCN)患者血清对正常淋巴细胞对于致丝裂素(mitogen)的反应的影响,作者检查了11例 MCN、14例膜性肾病和15......
Objective Mucus forms the physical barrier along the gastrointestinal(GI)tract.It plays an important role to prevent muc......
Obejctives To study mitogen activated protein kinase (MAPKs) activation in fibroblast like synoviocytes (FLS) of rheu......
期刊
THE LOCALIZATION OF ADRENOMEDULLIN IN RAT KIDNEY TISSUE AND ITS INHIBITORY EFFECT ON THE GROWTH OF C
Adrenomedullin（AM），anovelhypotensivepeptideoriginallyisolatedfromhumanpheochromocytoma（１），wassynthesizedinvarioustissues（２，３）．Thecalc......
AIM: To determine the possible role of pH in mediating activation of p38 mitogen-activated protein kinase (MAPK) and the......
Fetal rat models with neural tube defects were established by injection with retinoic acid at 10 days after conception. ......
Peroxisome proliferator-activated receptor-γ (PPAR-γ) is a transcription factor belonging to the nuclear receptor supe......
Effects of tetrandrine on phenotypic modulation of vascular smooth muscle cells and expression of p3
Objective: To study the effects of tetrandrine (Tet) on phenotypic modulation of vascular smooth muscle cells (VSMCs) an......
Increased expression of receptor for advanced glycation end-products worsens focal brain ischemia in
A rat model of diabetes mellitus was induced by a high fat diet,followed by focal brain ischemia induced using the threa......
Time-dependence of cardiomyocyte differentiation disturbed by peroxi-some proliferator-activated rec
Aim:To investigate the possible roles of peroxisome proliferator-activated recep-tor α(PPARα) and the signal pathway ......
Objective To investigation on novel pharmacological target against pulmonary hypertension.It was recognized in the recen......
Protein kinase small molecule inhibitors for rheumatoid arthritis: Medicinal chemistry/clinical pers
Medicinal chemistry strategies have contributed to the development, experimental study of and clinical trials assessment......
Xuebijing alters tumor necrosis factor-alpha, interleukin-1beta and p38 mitogen activated protein ki
We established a rat model of cardiac arrest by clamping the endotracheal tube of adult rats at expiration. Twenty-four ......
Phosphorylation of alphaB-crystallin in epiretinal membrane of human proliferative diabetic retinopa
AIM: To examine phosphorylation of alpha B-crystallin(p-αBC), a vascular endothelial growth factor(VEGF)chaperone, and ......
Lysophosphatidic acid(LPA) is a pleiotropic lipid mediator that promotes motility, survival, and the synthesis of chemok......
Activation of extracellular signal-regulated kinase by TGF-β1 via TβRⅡ and Smad 7 dependent mechanis
ObjectiveTransforming growth factor-β1(TGF-β1)can activate mitogen-activated protein kinases(MAPKs)inmanytypes of cell......
Omentin attenues oxidative stress-induced down-regulation of Ⅰ/Ⅳ collagen in the human aortic smooth
Objective To study the influence of omentin on the expression of collagenⅠ/Ⅳin the human aortic smooth muscle cells su......
目的探讨平阳霉素引发细胞凋亡与分裂原激活的蛋白激酶家族(mito gen-activated protein kinase,MAPK)信号转导通路的关联性.方法......
Effect of mitogen-activated protein kinase signal transduction pathway on multidrug resistance induc
AIM:To investigate the correlation between mitogen-activated protein kinase (MAPK) signal transduction pathwayand multi......
ORIGINALARTICLEDown-regulationofHsp90couldchangecellcycledistributionandincreasedrugsensitivityoftumorcells.MAJORPOINTSO......
INTRODUCTIONVascular endothelial growth factor(VEGF)whichis also known as vascular permeability factor(VPF)is a heparin......
CCK-8 inhibits expression of TNF-α in the spleen of endotoxic shock rats and sigual transduction mec
AIM:To study the effect of sulfated cholecystokinin-octapeptide(CCK-8)on systemic hypotension,gene andprotein expressio......
应用淋巴细胞丝裂原刺激后细胞~3H-TdR参入的方法,研究了小剂量γ射线照射(0～4 cGy)诱导淋巴细胞转化功能的适应性反应;探讨了影响......
Calcitonin gene-related peptide (CGRP), a neuropeptide contained in sensory neuron, has been demonstrated to be synthes......
Interleukin-1 beta up-regulates tissue inhibitor of matrix metalloproteinase-1 mRNA and phosphorylat
AIM: To study the relationship between interleu-kin-1beta (IL-1β) up-regulating tissue inhibitor of matrix metalloprote......
IL-1β activates p44/42 and p38 mitogen-activated protein kinases via different pathways in cat esoph
AIM:To examine the pathway related to the IL-1β-induced activation of mitogen-activated protein(MAP)kinases in cat eso......
Activation of phosphorylating-p38 mitogen-activated protein kinase and its relationship with localiz
AIM:To investigate the expression of phosphorylating p38mitogen-activated protein kinase (MAPK) in rat small intestinea......
Rapid mitogen-activated protein kinase by basic fibroblast growth factor in rat intestine after isch
AIM:Previous studies showed that exogenous basicfibroblast growth factor (bFGF or FGF-2) could improvephysiological dys......
4-hydroxy-2,3-nonenal activates activator protein-1 ant mitogen-activated protein kinases in rat pan
AIM:Activated pancreatic stellate cells (PSCs) are implicatedin the pathogenesis of pancreatic inflammation and fibrosi......
Protein kinase C-dependent activation of P44/42 mitogen-activated protein kinase and heat shock prot
AIM:To investigate the significance of protein kinase C(PKC),P44/42 mitogen-activated protein kinase (MAPKs)and heat sh......
Inhibition of p38 mitogen-activated protein kinase may decrease intestinal epithelial cell apoptosis
AIM: To investigate the role of p38 mitogen-activated protein kinase in rat small intestine after ischemia-reperfusion (......
AIM: To evaluate the effects of betaine on the ethanol-induced secretion of IGF-I and IGFBP-1 using radioim-munoassay an......
Inhibition of p38 mitogen-activated protein kinase attenuates experimental autoimmune hepatitis: Inv
AIM: To investigate the role of p38 mitogen-activated protein kinase (p38MAPK) in murine experimental autoimmune hepatit......
Ceramide from sphingomyelin hydrolysis differentially mediates mitogen-activated protein kinases (MA
Objective:To explore the role that ceramide plays in the activation of mitogen-activated protein kinases (MAPKs) during ......
Components of the mitogen-activated protein kinase cascade are activated in hepatic cells by Echinoc
AIM: To explore the effect of Echinococcus multilocularis (E. multilocularis) on the activation of mitogen-activated pro......
Involvement of mitogen-activated protein kinase pathways in N-methyl-D-aspartate-induced excitotoxic
Previous studies have shown that mitogen-activated protein kinase(MAPK) signaling pathways are involved in N-methyl-D-as......
Inhibiting p38 mitogen-activated protein kinase attenuates cerebral ischemic injury in Swedish mutan
Cerebral ischemia was induced using photothrombosis 1 hour after intraperitoneal injection of the p38 mitogen-activated ......
Signal transduction pathways in liver and the influence of hepatitis C virus infection on their acti
In liver,the most intensively studied transmembrane and intracellular signal transduction pathways are the Janus kinase ......
Oxygen free radical damage is regarded as a direct or indirect common pathway associated with diabetic neuropathy and is......
机体内有破坏并排除移植细胞、癌细胞、病毒感染细胞等的细胞。需要由靶细胞致敏和促分裂因子(mitogen)刺激,才能发挥细胞损伤作......
Studies have shown that sensory nerve damage can activate the p38 mitogen-activated protein kinase(MAPK)pathway,but whet......
The micro RNA(mi RNA) let-7 was one of the first mi RNAs to be discovered, and is highly conserved and widely expressed ......
根据抗原特异性,人干扰素(IFN)可以分为三种类型:IFN-α,IFN-β,IFN-γ。所有这三种类型又可按其理化性质和生物学特性上的差异进......
植物种子血凝素,例如从芸豆提取的植物血凝素(PHA),从刀豆提取的刀豆素A(Con.A)或从美洲商陆提取的商陆促有丝分裂因子(PWM)等等,......
T细胞mitogen可刺激T淋巴细胞产生IL-2和免疫干扰素(IFN-γ).IL-2具有使T细胞增殖并能刺激T细胞产生IFN-γ的作用.IL-2与IFN-γ之......
