N-Glycan相关论文
Analysis of Total N-Glycans in Cell Membrane and Cytosolic Fractions of Cancer Cells Using Mass Spec
N-glycans play important roles in cell differentiation,development,tumorigenesis,metastasis,and immunity.In this study,w......
Nonreductive chemical release of intact N-glycans for subsequent labeling and analysis by mass spect
A novel strategy is proposed, using cost-saving chemical reactions, to generate intact free reducing N-glycans and their......
Asparagine-linked glycans (N-glycans) are crucial signals for protein folding, sorting, and endoplasmic reticulum (ER)-a......
糖基化修饰是一种重要的蛋白质翻译后修饰，糖基化修饰在免疫反应、细胞识别、信号调控及蛋白降解等诸多生物过程中起着重要作用[1]......
目的：优化GlycoWorks HILIC SPE流程用于定量和稳定地从mAb型样品中回收N-Glycan.方法：采用了包含多种不同2-AB标记N-Glycan的测试混......
Microfluidic-based NanoLC/TOF for rapid and automated Characterization of N-linked Glycans from mono
Glycan profiles on monoclonal antibodies (mAbs) impact the therapeutic efficacy.Glycosylation is affected by many factor......
Novel N-linked Trisaccharide Decorates the S-layer Glycoproteins from the Halophilic Archaeon Haloar
Glycosylation is the most abundant and complex protein modifications in nature.First demonstrated in 1938 by Neuberger, ......
人血浆纤连蛋白（Ｆｉｂｒｏｎｅｃｔｉｎ，Ｆｎ）与人胎盘纤连蛋白两者在肽链结构上基本相同，但人血浆Ｆｎ的Ｎ－糖链结构为二天线结构，而人胎盘Ｆｎ不仅Ｎ－糖链的数量增加，同时还含有......
Effect of Bu-Zhong-Yi-Qi-Tang on deficiency of N-glycan/nitric oxide and islet damage induced by str
AIM: To investigate the effect of Bu-Zhong-Yi-Qi-Tang (Decoction for Reinforcing Middle Jiao and Replenishing Qi) on def......
,Trimming of N-Glycans by the Golgi-Localized α-1,2-Mannosidases, MNS1 and MNS2, Is Crucial for Main
Asparagine (Asn/N)-Iinked glycans are important for protein folding,trafficking,and endoplasmic reticulum-associated deg......
Effect of Bu-Zhong-Yi-Qi-Tang on deficiency of N-glycan/nitric oxide and islet damage induced by str
AIM: To investigate the effect of Bu-Zhong-Yi-Qi-Tang (Decoction for Reinforcing Middle Jiao and Replenishing Qi) on def......
免疫球蛋白(Ig)在人体抵抗外部感染和对自身异常细胞的监控、清除中扮演重要角色,位于IgG Fc段的N-聚糖在调节IgG的炎症活性上起到......
利用酿酒酵母（Saccharomyces cerevisiae）生产医药糖蛋白,必须对其N-糖基化途径进行人源化改造。在敲除酿酒酵母W303A特异性糖基化基......
为了优化利用N糖苷酶F(PNGase F)酶解单克隆抗体中N糖的方法,应用本公司生产的单抗对PNGase F酶的酶解条件进行优化,包括缓冲液pH......
上皮间质转化（Epithelial mesenchymal transition，EMT）是肿瘤发展的重要过程，肿瘤细胞与良性细胞间的信息传递能够促进肿瘤的发展。由......
基于化学酶标记和丙酮富集糖肽方法,建立了一种可靠、有效、简单的糖蛋白N-糖链分析方法。以唾液酸糖肽(SGP)为模型糖肽,比较了样......
以β-伴大豆球蛋白（β-conglycinin）为研究对象,利用Trypsin和Pepsin酶对其进行水解,以Con A亲和层析柱富集纯化糖肽,并用糖苷酶PNGa......
从皮肤成纤维细胞张地连蛋白及其片段Ｎ－糖链结构。用明胶－Ｓｅｐｈａｒｏｓｅ４Ｂ亲和柱纯化培养的人皮肤成纤维细胞所分泌的纤连蛋白，用胰糜蛋白酶限制性水解......
Three human α-amylases exist: Amy1 (salivary amylase), Amy2A (pancreatic amylase), and Amy2B (expressed in various tiss......
目的：检测苦马豆素对骨肉瘤类肿瘤干细胞（CSCs）N-糖链表达的影响。方法：通过无血清培养法培养小鼠骨肉瘤细胞株LM8，经磁珠细胞分选技术......
糖蛋白(glycoprotein)是一类广泛存在于真核生物中,由寡糖和多肽链共价修饰连接而形成的重要生理活性物质,绝大多数以N-糖基化的形......
ue＊M＃’＃dkB4＃＃8＃”专利申请号:00109“7公开号:1278062申请日:00.06.23公开日:00.12.27申请人地址:（100084川C京市海淀区清华园申请人:清......
BACKGROUND Hepatitis B virus (HBV) infection is the primary cause of hepatitis with chronic HBV infection,which may deve......
目的:异常糖基化与癌症的发展密切相关,可以用来作为癌症的一个确定的标志。本实验的目的是运用糖组学的研究方法,发现乳腺癌患者......
