RADIOSENSITIVITY相关论文
Polygenic risk score for prediction of radiotherapy efficacy and radiosensitivity in patients with n
Objective:Toconstructanovelpolygenicriskscoringmodel,inordertopredictthebenefitsofradiosensitivityinpatientswithnon-meta......
目的:探究SUMO E3连接酶(zinc finger protein 451,ZNF451)介导非小细胞肺癌A549细胞和宫颈癌HeLa细胞DNA损伤修复的功能及机制。方......
目的:探讨TAB182促进同源重组(HR)修复的相关调控分子及机制。方法:利用shRNA敲低人乳腺癌MCF-7细胞中的TAB182基因,TAB182敲低的MC......
Salicylic acid sensitizes cervical cancer cells to radiotherapy by activating AMPK/TSC2/mTOR pathway
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To Predict the Radiosensitivity of Nasopharyngeal Carcinoma using Intravoxel Incoherent Motion MRI a
Purpose: To investigate intravoxel incoherent motion(IVIM)for evaluating the sensitivity of radiotherapy of nasopharynge......
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目的 Osteosarcoma is a malignant bone tumor and is generally treated with radiotherapy combined with radiosensitizers.Th......
Microwave hyperthermia increases sensitivity to radiation in highly invasive human non-small cell lu
Objective Non-small cell lung carcinomas(NSCLCs)comprise approximately 85%of lung cancers and have an overall 5-year sur......
Objective Signal transducer and activator of transcription(STAT)is an important nucleic acid transcription factor.It is ......
Objective Radioresistance is the main problem for treatment of colorectal carcinoma.Potatoes are rich in eight essential......
Cordycepin sensitizes breast cancer cells toward irradiation through elevating ROS production involv
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Objective The gut microbiota is known to affect digestion,protection against pathogens infection,immune system maturatio......
IDH1R132H mutation induces a less aggressive phenotype of glioma cells and affects the radiosensitiv
Objective Gliomas are often found to contain mutations in the isocitrate dehydrogenase 1(IDH1)gene,and the most common t......
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Enhancement of radiosensitivity by MLN4924, a specific Nedd8-activating enzyme inhibitor, in prostat
Objective: The study aims at investigating the radiosensitivity induced by MLN4924, a specific Nedd8-activating enzyme i......
Objective: To investigate the effect of elemene on the radiosensitivity of A549 cells and its possible molecular mechani......
Caveolin-1 targeting by its shRNA enhances human hepatocyte response to X-ray radiation through p53-
Caveolin-1(Cav-1),as an important structural protein of caveolae,has been proved to be correlated with several signal tr......
Purpose:Autophagy is the major regulated mechanism for degrading long lived proteins and the only known pathway for degr......
Objective: Proteinkinase CK2 (also known ascasein kinase) is a highlyconserved seine/threonine protein kinase, which is ......
The primary objective of the current study is to define the role of miRNA-320 in determining sensitivity of cervical can......
Purpose: Cell-free circulating DNA in plasma has served widely as a biomarker for predicting many diseases including can......
Inhibiting glucose transporter-1 and the PI3K/Akt pathway with apigenin, siRNA, LY294002 or wortmann
Background We first hypothesized that targeting glucose transporter-1 (GLUT-1) and the phosphatidylinositol 3-kinase/pro......
MicroRNA-153/Nrf-2/GPx1 pathway regulates radiosensitivity and stemness of glioma stem cells via rea
Glioma stem cells (GSCs) exhibit stem cell properties and high resistance to radiotherapy.Reactive oxygen species (ROS) ......
Molecular target-based drugs have been emerging as a cancer treatment, and clinical trials using combined approach of ra......
Targeting EBV-LMP1 DNAzyme Enhances Radiosensitivity of Nasopharyngeal Carcinoma Cells by Inhibiting
The latent membrane protein 1 (LMP1),which is encoded by the Epstein-Barr virus (EBV) has been suggested to be one of th......
Suppression of Telomere-Binding Protein TPPI Resulted in Telomere Dysfunction and Enhanced Radiation
Mammalian telomeres are protected by the shelterin complex that contains the six core proteins POT 1, TPP1, TIN2, TRF1, ......
c-Met inhibitor SU11274 enhances the response of the prostate cancer cell line DU145 to ionizing rad
Hormone-refractory prostate cancer shows substantial resistance to most conventional therapies includ ing radiotherapy, ......
Verapamil Enhances the Radiosensitivity of Lung cancer Cells through Inhibiting PKC and NF-κB Signal
Radiotherapy is still an effective approach to treat lung cancer.Clinically,effectiveness of radiotherapy weakened by re......
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With the development of modern computing technology and medical physics, radiotherapy has made great progress. The theor......
ObjectiveLung cancer cells associated with radioresistance are likely to give rise to local recurrence and distant metas......
Histone deacetylase inhibitor, 2-propylpentanoic acid, increases the chemosensitivity and radiosensi
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ObjectiveTo study the nuclear protein association of high-mobility group box-1(HMGB1) and histone deacetylase 1(HDAC1), ......
目的研究下调lncRNA LINC00263靶向miR-4458对乳腺癌SK-BR-3细胞增殖、运动、侵袭及放射敏感性影响。方法qRT-PCR方法分别检测乳腺......
目的探索miR-205-5p/E2F1信号轴在脑胶质瘤U251、U87细胞放射耐受中的调控机制。方法利用X射线逐步递增递间歇诱导方法照射U251、U......
目的探究circ_0023990对甲状腺癌细胞放射敏感性的影响及可能机制。方法采用逆转录聚合酶链反应(qRT-PCR)法检测2016年8月至2018年11......
目的探究LncRNA BBOX1-AS1在卵巢癌(ovarian cancer,OC)放疗敏感性中的作用及潜在机制。方法qRT-PCR检测OC组织和细胞中BBOX1-AS1、mi......
目的探讨沉默FAM83D对X线照射后食管鳞状细胞癌(ESCC)细胞增殖、存活能力及侵袭、迁移能力的影响及机制。方法采用免疫组化法检测6......
目的探讨circ_0001955对前列腺癌DU145细胞系放射敏感性的影响及分子机制。方法将si-con、si-circ_0001955、miR-con、miR-149转染......
目的探讨Myosin X对肺癌H1975细胞系放射敏感性调节及相关机制。方法蛋白免疫印迹法检测肺癌细胞系中Myosin X表达量以获取实验对......
目的 探讨抑制miR-21表达对SHG-44人脑胶质瘤细胞系放射敏感性的影响及其机制.方法 脂质体介导采用瞬间转染法转染反义miR-21寡核......
目的 研究蒿甲醚(artemether)对人鼻咽癌CNE-1细胞放射敏感性的影响及其作用机理.方法 用MTT法检测蒿甲醚对CNE-1细胞生长的抑制效应......
目的构建靶向生存素(survivin)基因的RNA干扰(RNAi)载体,观察对肺腺癌A549细胞放射敏感性的影响,并探讨其机制。方法根据survivin的cDNA......
目的 探讨LncRNA OIP5-AS1对非小细胞肺癌放射抗拒细胞A549R的放射敏感性影响及作用机制.方法 X射线6Gy照射5次A549细胞建立放射抗......
目的 探讨IncRNA GIHCG对胶质瘤细胞放射敏感性的影响及作用机制.方法 qRT-PCR实验检测人脑正常胶质细胞HEB和胶质瘤细胞系U251、A......
BACKGROUND: Progenitors of the immortalized human glioma cell line, SHG-44, are significantly less sensitive to irradiat......
目的 探讨二甲双胍对肺癌A549细胞的放射增敏作用及其潜在的机制.方法 采用CCK-8法检测不同浓度二甲双胍对A549细胞的抑制作用,计......
目的 探讨microRNA-153对(miR-153)对脑膜瘤细胞放疗敏感性的影响及其作用机制.方法 采用实时荧光定量聚合酶链反应检测放疗前后脑......
Cell survival curve for primary hepatic carcinoma cells and relationship between SF2 of hepatic carc
AIM: To establish the cell survival curve for primary hepatic carcinoma cells and to study the relationship between SF2 ......