TACI-Ig相关论文
BLyS participate in the interaction between T and B cells in collagen-induced arthritis mice and the
Aim: To investigate the role of B lymphocyte stimulator (BLyS) on the interaction between T and B cells in collagen-indu......
Therapeutic effects of TACI-Ig on rats with adjuvant-induced arthritis via regulating T cell-mediate
OBJECTIVE To investigate the effects of TACI-Ig, a recombinant fusion protein that modulates B and T cells activation by......
Comparative efficacy of TACI-Ig with TNF-α inhibitor and methotrexate in DBA/1 mice with collagen-in
OBJECTIVE TACI-Ig, a BlyS inhibitor, is a new biologic agent in treatment for RA.The effective differences of TACI-Ig wi......
APRIL PROMOTES PROLIFERATION, SECRETION AND INVASION OF FIBROBLAST-LIKE SYNOVIOCYTE FROM RATSWITH AD
Fibroblast-like synoviocyte (FLS) is the ultimate effectual cells in the pathogenesis of rheumatoid arthritis (RA).The c......
Abnormal expression of BLyS/APRIL and receptors in synovium tissue mediate T cell responses in adjuv
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目的:研究跨膜激活剂及钙调亲环素配体相互作用分子的免疫球蛋白对rhBLyS刺激佐剂性关节炎大鼠肠系膜淋巴结细胞功能的影响.方法:r......
系统性红斑狼疮(systemic lupus erythematosus, SLE)是一种涉及多基因、多系统和多器官受累的自身免疫病,严重威胁了人类健康。SL......
目的研究TACI-Ig对MRL/lpr小鼠的治疗作用以及TACI-Ig对狼疮性肾炎肾组织JAK1-STAT1信号通路活化的影响。方法将MRL/lpr红斑狼疮转......
目的研究TACI-Ig对MRL/lpr小鼠的治疗作用以及TACI-Ig对狼疮性肾炎肾组织JAK1-STAT1信号通路活化的影响。方法将MRL/lpr红斑狼疮转......
目的研究泼尼松和跨膜激活和钙调和亲环素配体相互作用因子融合蛋白(TACI-Ig)联合用药对系统性红斑狼疮MRL/Mpslac-lpr(MRL/lpr)小鼠的治......
目的研究TACI受体融合蛋白(TACI-Ig)对T细胞介导的免疫性关节炎的调节作用,探讨其调控T细胞反应的部分机制。方法 SD大鼠右后足跖......
B淋巴细胞刺激因子(B lymphocyte stimulator, BLyS)是肿瘤坏死因子超家族成员之一,主要来源于骨髓家族细胞包括单核细胞、巨噬细......
类风湿关节炎(rheumatoid arthritis, RA)是一种慢性、炎症性、系统性自身免疫病。T、B淋巴细胞的紊乱在RA的病程进展中发挥着重要......
<正>目的:观察TACI-Ig体外对B淋巴细胞功能的影响,进一步阐明TACI-Ig的作用机制。方法:采用重组人B淋巴细胞刺激因子(B lymphocyte......